Tracking SARS-CoV-2 Omicron diverse spike gene mutations identifies multiple inter-variant recombination events

J Ou, W Lan, X Wu, T Zhao, B Duan, P Yang… - … and Targeted Therapy, 2022 - nature.com
The current pandemic of COVID-19 is fueled by more infectious emergent Omicron variants.
Ongoing concerns of emergent variants include possible recombinants, as genome …

[HTML][HTML] Molecular insights into the adaptive evolution of SARS-CoV-2 spike protein

Z Yao, L Zhang, Y Duan, X Tang, J Lu - Journal of Infection, 2024 - Elsevier
The COVID-19 pandemic, caused by the severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2), has substantially damaged the global economy and human health. The …

Advances in pathogenesis, progression, potential targets and targeted therapeutic strategies in SARS-CoV-2-Induced COVID-19

H Zhou, WJ Ni, W Huang, Z Wang, M Cai… - Frontiers in …, 2022 - frontiersin.org
As the new year of 2020 approaches, an acute respiratory disease quietly caused by severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), also known as coronavirus …

Adaptive evolution of the spike protein in coronaviruses

X Tang, Z Qian, X Lu, J Lu - Molecular Biology and Evolution, 2023 - academic.oup.com
Coronaviruses are single-stranded, positive-sense RNA viruses that can infect many
mammal and avian species. The Spike (S) protein of coronaviruses binds to a receptor on …

[HTML][HTML] Suitability of aircraft wastewater for pathogen detection and public health surveillance

DL Jones, JM Rhymes, MJ Wade, JL Kevill… - Science of The Total …, 2023 - Elsevier
International air travel is now widely recognised as one of the primary mechanisms
responsible for the transnational movement and global spread of SARS-CoV-2. Monitoring …

Quantitative profiling of N-glycosylation of SARS-CoV-2 spike protein variants

Y Xie, M Butler - Glycobiology, 2023 - academic.oup.com
With the global spread of the corona virus disease-2019 pandemic, new spike variants of
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continuously emerge due …

The runaway evolution of SARS-CoV-2 leading to the highly evolved Delta strain

Y Ruan, M Hou, X Tang, X He, X Lu, J Lu… - Molecular Biology …, 2022 - academic.oup.com
In new epidemics after the host shift, the pathogens may experience accelerated evolution
driven by novel selective pressures. When the accelerated evolution enters a positive …

VirusRecom: an information-theory-based method for recombination detection of viral lineages and its application on SARS-CoV-2

ZJ Zhou, CH Yang, SB Ye, XW Yu… - Briefings in …, 2023 - academic.oup.com
Genomic recombination is an important driving force for viral evolution, and recombination
events have been reported for severe acute respiratory syndrome coronavirus 2 (SARS-CoV …

Detection of Circulating SARS-CoV-2 Variants of Concern (VOCs) Using a Multiallelic Spectral Genotyping Assay

AC Chrysostomou, A Aristokleous, JH Rodosthenous… - Life, 2023 - mdpi.com
Throughout the coronavirus disease 2019 (COVID-19) pandemic, severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) has continuously evolved, resulting in new variants …

Evolution of Sequence and Structure of SARS-CoV-2 Spike Protein: A Dynamic Perspective

A Sinha, S Sangeet, S Roy - ACS omega, 2023 - ACS Publications
Novel coronavirus (SARS-CoV-2) enters its host cell through a surface spike protein. The
viral spike protein has undergone several modifications/mutations at the genomic level …