Pathophysiology of polycystic ovary syndrome revisited: Current understanding and perspectives regarding future research

M Harada - Reproductive medicine and biology, 2022 - Wiley Online Library
Background Polycystic ovary syndrome (PCOS) is the most common endocrine disorder
among reproductive‐age women and has lifelong effects on health. Methods In this review, I …

[HTML][HTML] Advances in the interaction between endoplasmic reticulum stress and osteoporosis

M Zhong, Z Wu, Z Chen, Q Ren, J Zhou - Biomedicine & Pharmacotherapy, 2023 - Elsevier
The endoplasmic reticulum (ER) is the main site for protein synthesis, folding, and secretion,
and accumulation of the unfolded/misfolded proteins in the ER may induce ER stress. ER …

Roles of endoplasmic reticulum stress in the pathophysiology of polycystic ovary syndrome

H Koike, M Harada, A Kusamoto, Z Xu… - Frontiers in …, 2023 - frontiersin.org
Polycystic ovary syndrome (PCOS) is the most common endocrine disorder among
reproductive-age women, affecting up to 15% of women in this group, and the most common …

[HTML][HTML] Undesirable ER stress induced by bavachin contributed to follicular atresia in zebrafish ovary

CS Huang, HF Deng, L Zhou, P Shen, YH Ni… - Biomedicine & …, 2023 - Elsevier
Fructus psoraleae (FP) is a commonly used herb with potential reproductive toxicity.
Bavachin (BV), one of essential active ingredients of FP, was found to exhibit estrogenic …

Advancements in lead therapeutic phytochemicals polycystic ovary syndrome: A review

ED Luo, HM Jiang, W Chen, Y Wang, M Tang… - Frontiers in …, 2023 - frontiersin.org
Polycystic ovary syndrome (PCOS) is one of the most common endocrine diseases in
women of reproductive age and features complex pathological symptoms and mechanisms …

Moderate aerobic Exercise regulates follicular dysfunction by initiating brain-derived neurotrophic factor (BDNF)-Mediated anti-apoptotic signaling pathways in …

Y Zhang, D Chen, D Wang, L Wang, Y Weng… - Journal of Clinical …, 2022 - mdpi.com
Polycystic ovary syndrome (PCOS) is a common endocrine disorder among women.
Moderate aerobic exercise intervention is considered an initial treatment strategy for …

Insights on the NF-κB system in polycystic ovary syndrome, attractive therapeutic targets

W Tan, J Zhang, F Dai, D Yang, R Gu, L Tang… - Molecular and Cellular …, 2024 - Springer
The nuclear factor κappa B (NF-κB) signaling plays a well-known function in inflammation
and regulates a wide variety of biological processes. Low-grade chronic inflammation is …

The effects of natural products and bioactive ingredients of traditional Chinese medicine on apoptosis of ovarian granulosa cells

L Zhong, Y Luo, F Zhou, X Yang, Y Tan… - Journal of Applied …, 2023 - Wiley Online Library
Abnormal ovarian function is the main manifestation of female reproductive toxicity.
Granulosa cells (GCs) play an important role in determining the fate of follicles and are the …

The mechanism of curcumin to protect mouse ovaries from oxidative damage by regulating AMPK/mTOR mediated autophagy

H Duan, S Yang, S Yang, J Zeng, Z Yan, L Zhang, X Ma… - Phytomedicine, 2024 - Elsevier
Background Oxidative stress is considered the main cause of granulosa cell apoptosis in
ovarian disease. Curcumin has various biological roles, but its potential role in protecting …

[PDF][PDF] Effect of Curcumin (Standard and Supplement) with Zinc on Reproductive Hormones in Polycystic Ovary Syndrome (PCOS) Rats.

SM Abd-Alqader, SA Zearah… - Tropical Journal of …, 2023 - faculty.uobasrah.edu.iq
Polycystic ovary syndrome (PCOS) is a complex and heterogeneous disorder that affects a
large percentage of women worldwide. The pathophysiology is not fully explained. In recent …