Nuclear receptor crosstalk can be defined as the interplay between different nuclear
receptors or between their overlapping signalling pathways. A subset of nuclear receptors …

Male breast cancer (MBC) is rare, accounting for less than 1% of all breast cancer but the
incidence has increased worldwide. Risk factors include increased longevity, obesity …

SARS-CoV-2 attacks various organs, most destructively the lung, and cellular entry requires
two host cell surface proteins: ACE2 and TMPRSS2. Downregulation of one or both of these …

Male breast cancer (MBC) is a rare but aggressive malignancy with cellular and
immunological characteristics that remain unclear. Here, we perform transcriptomic analysis …

Abstract The Androgen Receptor (AR) is the key-driving transcription factor in prostate
cancer, tightly controlled by epigenetic regulation. To date, most epigenetic profiling has …

Skeletal muscle mass, strength, and regenerative capacity decline with age, with many
measures showing a greater deterioration in females around the time estrogen levels …

Simple Summary Factors such as estrogen, progesterone, and androgen receptors, also
known as nuclear receptors, are abundantly expressed in the majority of breast cancers …

Glucocorticoid receptor (GR) is a transcription factor that plays a crucial role in cancer
biology. In this study, we utilized an in silico‐designed GR activity signature to demonstrate …

Although similar phenotypically, there is evidence that male and female breast cancer differ
in their molecular landscapes. In this systematic review, we consolidated all existing …

Steroid hormone receptors (SRs) have a multitude of functions in human biology and
disease progression. The SR family of related ligand-activated transcription factors includes …