Chromatin accessibility, or the physical access to chromatinized DNA, is a widely studied
characteristic of the eukaryotic genome. As active regulatory DNA elements are generally …

Wild animals and plants have developed a variety of adaptive traits driven by adaptive
evolution, an important strategy for species survival and persistence. Uncovering the …

For decades, budding yeast, a single-cellular eukaryote, has provided remarkable insights
into human biology. Yeast and humans share several thousand genes despite …

The planarian Schmidtea mediterranea is being studied as a model species for
regeneration, but the assembly of planarian genomes remains challenging. Here, we report …

Little is known about the extent to which species use homologous regulatory architectures to
achieve phenotypic convergence. By characterizing chromatin accessibility and gene …

Although lifespan in mammals varies over 100-fold, the precise evolutionary mechanisms
underlying variation in longevity remain unknown. Species-specific genetic changes have …

Snakes are a remarkable squamate lineage with unique morphological adaptations,
especially those related to the evolution of vertebrate skeletons, organs, and sensory …

Background The genetic mechanisms that underlie phenotypic differentiation in breeding
animals have important implications in evolutionary biology and agriculture. However, the …

After the loss of a trait, theory predicts that the molecular machinery underlying its
phenotypic expression should decay. Yet, empirical evidence is contrasting. Here, we test …

Conserved cis-regulatory elements (CREs) control Engrailed-, Pax2-, and dachshund-
related gene expression networks directing the formation and function of corresponding …