Nuclear localization signals (NLS) are generally short peptides that act as a signal fragment
that mediates the transport of proteins from the cytoplasm into the nucleus. This NLS …

The 2022 WHO classification reflects increases in the knowledge of the underlying
pathogenesis of parathyroid disease. In addition to the classic characteristic features of …

Long non-coding RNAs (lncRNAs) are a class of RNA transcripts more than 200 nucleotides
in length that play crucial roles in cancer development and progression. With the rapid …

Parathyroid carcinoma is a rare endocrine malignancy. The reported incidence is from 0.5 to
5% of primary hyperparathyroidism cases in various series. The cause is unknown, but …

Introduction Parathyroid carcinoma (PC) is a rare endocrine disorder, commonly causing
severe primary hyperparathyroidism (PHPT). PC is mainly a sporadic disease, but it may …

Dr Marcocci claims a consultancy and lists himself as a member of the international advisory
board for Amgen. Dr Bilezikian has served as a consultant to Merck, Lilly, Amgen, NpS …

Recent data suggest an increase in the overall incidence of parathyroid disorders, with
primary hyperparathyroidism (PHPT) being the most prevalent parathyroid disorder. PHPT is …

The hyperparathyroidism‐jaw tumor (HPT‐JT) syndrome is an autosomal dominant disorder
characterized by the occurrence of parathyroid tumors in association with ossifying fibromas …

Parathyroid carcinoma (PC) may occur as part of a complex hereditary syndrome or an
isolated (ie, non‐syndromic) non‐hereditary (ie, sporadic) endocrinopathy. Studies of …

The majority of parathyroid disease encountered in routine practice is due to single
parathyroid adenoma, of which the majority arise as sporadic tumors. This is usually a …