APOL1-G2 accelerates nephrocyte cell death by inhibiting the autophagy pathway
People of African ancestry who carry the APOL1 risk alleles G1 or G2 are at high risk of
developing kidney diseases through not fully understood mechanisms that impair the …
developing kidney diseases through not fully understood mechanisms that impair the …
[HTML][HTML] Actin Cytoskeleton and Integrin Components Are Interdependent for Slit Diaphragm Maintenance in Drosophila Nephrocytes
In nephrotic syndrome, the podocyte filtration structures are damaged in a process called
foot process effacement. This is mediated by the actin cytoskeleton; however, which actins …
foot process effacement. This is mediated by the actin cytoskeleton; however, which actins …
Spatial Dynamics of the Developing Human Heart
E Lázár, R Mauron, Ž Andrusivová, J Foyer, M He… - bioRxiv, 2024 - biorxiv.org
Heart development relies on a topologically defined interplay between a diverse array of
cardiac cells. We finely curated spatial and single-cell measurements with subcellular …
cardiac cells. We finely curated spatial and single-cell measurements with subcellular …
Distinct Roles for COMPASS Core Subunits Set1, Trx, and Trr in the Epigenetic Regulation of Drosophila Heart Development
Highly evolutionarily conserved multiprotein complexes termed Complex of Proteins
Associated with Set1 (COMPASS) are required for histone 3 lysine 4 (H3K4) methylation …
Associated with Set1 (COMPASS) are required for histone 3 lysine 4 (H3K4) methylation …
Single-cell RNA sequencing reveals the gene expression profile and cellular communication in human fetal heart development
X Hou, X Si, J Xu, X Chen, Y Tang, Y Dai, F Wu - Developmental Biology, 2024 - Elsevier
The heart is the central organ of the circulatory system, and its proper development is vital to
maintain human life. As fetal heart development is complex and poorly understood, we use …
maintain human life. As fetal heart development is complex and poorly understood, we use …
[HTML][HTML] 果蝇心脏发育研究三十年进展
袁婺洲， 谢玉莲， 吴秀山， 邓婷智， 苏梦岚… - 生命科学 …, 2024 - smkx.hunnu.edu.cn
果蝇(Drosophila melanogaster) 作为最早用于研究心脏发育基因调控的模式生物,
已经走过三十年的历程. 果蝇心脏发育过程经历了胚胎期, 幼虫期和成虫期三大阶段 …
已经走过三十年的历程. 果蝇心脏发育过程经历了胚胎期, 幼虫期和成虫期三大阶段 …
[PDF][PDF] Thirty Years' Progress in the Study of Drosophila Heart Development
W YUAN, Y XIE, X WU, T DENG - Life Science Research - smkx.hunnu.edu.cn
Over the past three decades, Drosophila melanogaster has emerged as a leading model
organism to investigate the regulatory mechanism of heart development. The development …
organism to investigate the regulatory mechanism of heart development. The development …