[HTML][HTML] Solid implantable devices for sustained drug delivery

E Magill, S Demartis, E Gavini, AD Permana… - Advanced Drug Delivery …, 2023 - Elsevier
Implantable drug delivery systems (IDDS) are an attractive alternative to conventional drug
administration routes. Oral and injectable drug administration are the most common routes …

Emerging biomaterial-based strategies for personalized therapeutic in situ cancer vaccines

DI Viswanath, HC Liu, DP Huston, CYX Chua… - Biomaterials, 2022 - Elsevier
Landmark successes in oncoimmunology have led to development of therapeutics boosting
the host immune system to eradicate local and distant tumors with impactful tumor reduction …

Biomedical resin reinforced with Cellulose Nanofibers (CNF) in VAT photopolymerization (VPP) Additive Manufacturing (AM): The effect of filler loading and process …

N Vidakis, M Petousis, CN David, D Sagris… - Journal of Manufacturing …, 2023 - Elsevier
Cellulose Nanofibers (CNF) are excellent reinforcement agents for biomedical resins in VPP
3D printing. However, the impact of process parameters on CQIs of VPP-fabricated …

Multifunctional medical grade resin with enhanced mechanical and antibacterial properties: the effect of copper nano-inclusions in vat polymerization (VPP) additive …

N Vidakis, M Petousis, VM Papadakis… - Journal of Functional …, 2022 - mdpi.com
Vat photopolymerization (VPP) is an additive manufacturing process commonly used in
medical applications. This work aims, for the first time in the literature, to extend and …

Recent Progress in Implantable Drug Delivery Systems

GQ He, H Li, J Liu, YL Hu, Y Liu, ZL Wang… - Advanced …, 2024 - Wiley Online Library
In recent years, tremendous effort is devoted to developing platforms, such as implantable
drug delivery systems (IDDSs), with temporally and spatially controlled drug release …

Nanocarrier design for pathogen-inspired innate immune agonist delivery

GI Kane, ML Brassil, MB Diaz-Infante… - Trends in Immunology, 2024 - cell.com
In complex diseases such as cancer, modulating cytokine signatures of disease using innate
immune agonists holds therapeutic promise. Novel multi-agonist treatments offer tunable …

Implantation of In Situ Gelling Systems for the Delivery of Chemotherapeutic Agents

EO Bakhrushina, IB Mikhel, LM Buraya, ED Moiseev… - Gels, 2024 - mdpi.com
Implantation is a modern method of administering chemotherapeutic agents, with a highly
targeted effect and better patient tolerance due to the low frequency of administration …

[HTML][HTML] Localization of drug biodistribution in a 3D-bioengineered subcutaneous neovascularized microenvironment

S Capuani, N Hernandez, J Paez-Mayorga, P Dogra… - Materials Today Bio, 2022 - Elsevier
Local immunomodulation has shown the potential to control the immune response in a site-
specific manner for wound healing, cancer, allergy, and cell transplantation, thus abrogating …

A miniaturized genotoxicity evaluation system for fast biomaterial-related risk assessment

V Gribova, JMA Dominguez, A Morin, JS Diaz… - Analytical …, 2023 - pubs.rsc.org
Implants and prostheses are widely used to either repair damaged tissues or treat different
diseases. Before an implant reaches the market, multiple preclinical and clinical tests must …

Implantable Biomaterials for Cancer Immunotherapies

NA Pechnikova, A Aggeli, AA Latypova… - Advanced Functional …, 2024 - Wiley Online Library
Cancer immunotherapy has revolutionized cancer treatment by leveraging the immune
system to target and eliminate tumor cells. Implantable biomaterials, such as hydrogels …