Natural products have long been an important source for discovery of new drugs to treat
human diseases. Piperlongumine (PL) is an amide alkaloid isolated from Piper longum …

Infections caused by parasitic helminths rank among the most prevalent infections of
humans and animals. Toxocariasis, caused by nematodes of the genus Toxocara, is one of …

Since praziquantel is the only drug available to treat schistosomiasis, a neglected parasitic
disease that affects more than 240 million people worldwide, there is an urgent demand for …

Ethnopharmacological relevance Propolis has been used in folk medicine for thousands of
years and, in the past few decades, it has attracted renewed interest. Although propolis has …

The chemical classes of semicarbazones, thiosemicarbazones, and hydrazones are present
in various compounds, each demonstrating diverse biological activities. Extensive studies …

Piplartine (or Piperlongumine) is a natural alkaloid isolated from Piper longum L., which has
been proposed to exhibit various biological properties such as anti-inflammatory effects; …

Schistosomiasis is a widespread human parasitic disease currently affecting over 200
million people, particularly in poor communities. Chemotherapy for schistosomiasis relies …

Schistosomiasis, a parasitic disease caused by the blood fluke of the genus Schistosoma,
affects over 230 million people, especially in developing countries. Despite the significant …

Schistosomiasis, a parasitic disease affecting nearly 250 million individuals globally, poses
a significant health challenge. With praziquantel being the sole available treatment and its …

Background Schistosomiasis, caused by the parasitic blood fluke Schistosoma mansoni, is a
significant global health concern, particularly in tropical and subtropical regions. The …