Rats and mice have been demonstrated to show episodic-like memory, a prototype of
episodic memory, as defined by an integrated memory of the experience of an object or …

Highlights•We review classical ideas on entorhinal–hippocampal structure and
function.•Recent data on cell-type specific entorhinal inputs radically change these …

Temporal lobe epilepsy causes severe cognitive deficits, but the circuit mechanisms remain
unknown. Interneuron death and reorganization during epileptogenesis may disrupt the …

Theta oscillations play a major role in temporarily defining the hippocampal rate code by
translating behavioral sequences into neuronal representations. However, mechanisms …

Memory traces are reactivated selectively during sharp-wave ripples. The mechanisms of
selective reactivation, and how degraded reactivation affects memory, are poorly …

Abstract Cajal-Retzius cells (CRs) are transient neurons, disappearing almost completely in
the postnatal neocortex by programmed cell death (PCD), with a percentage surviving up to …

Electrical brain stimulation has become an essential treatment option for more than one third
of epilepsy patients who are resistant to pharmacological therapy and are not candidates for …

Understanding brain operation demands linking basic behavioral traits to cell-type specific
dynamics of different brain-wide subcircuits. This requires a system to classify the basic …

Dravet syndrome (DS) is an epileptic encephalopathy that still lacks biomarkers for
epileptogenesis and its treatment. Dysfunction of Na V 1.1 sodium channels, which are …

Abnormal N-methyl-D-aspartate receptor (NMDAr) function has been linked to
oscillopathies, psychosis, and cognitive dysfunction in schizophrenia (SCZ). Here, we …