Gradient boosting decision tree-based method for predicting interactions between target genes and drugs
Determining the target genes that interact with drugs—drug–target interactions—plays an
important role in drug discovery. Identification of drug–target interactions through biological …
important role in drug discovery. Identification of drug–target interactions through biological …
InfAcrOnt: calculating cross-ontology term similarities using information flow by a random walk
Background Since the establishment of the first biomedical ontology Gene Ontology (GO),
the number of biomedical ontology has increased dramatically. Nowadays over 300 …
the number of biomedical ontology has increased dramatically. Nowadays over 300 …
Predicting disease-related genes using integrated biomedical networks
Background Identifying the genes associated to human diseases is crucial for disease
diagnosis and drug design. Computational approaches, esp. the network-based …
diagnosis and drug design. Computational approaches, esp. the network-based …
A novel method to measure the semantic similarity of HPO terms
It is critical yet remains to be challenging to make precise disease diagnosis from complex
clinical features and highly heterogeneous genetic background. Recently, phenotype …
clinical features and highly heterogeneous genetic background. Recently, phenotype …
Predicting sub-golgi apparatus resident protein with primary sequence hybrid features
C Wang, J Li, X Liu, M Guo - Ieee Access, 2019 - ieeexplore.ieee.org
The Golgi apparatus is a significant membrane-bound organelle of eukaryotic cells that is
made up of a series of flattened, stacked pouches (called cisternae). The Golgi apparatus …
made up of a series of flattened, stacked pouches (called cisternae). The Golgi apparatus …
[HTML][HTML] A framework for exploring associations between biomedical terms in PubMed
Co-occurrence relationships in PubMed between terms accelerate the recognition of term
associations. The lack of manually curated relationships in vocabularies and the rapid …
associations. The lack of manually curated relationships in vocabularies and the rapid …