Astrocytes are highly complex cells that respond to a variety of external stimulations. One of
the chief functions of astrocytes is to optimize the interstitial space for synaptic transmission …

Glutamate is the principal excitatory neurotransmitter of the central nervous system, but
many studies have expanded its functional repertoire by showing that glutamate receptors …

Apoptosis, a type of genetically controlled cell death, is a fundamental cellular mechanism
utilized by multicellular organisms for disposal of cells that are no longer needed or …

Until recently, anion (Cl−) channels have received considerably less attention than cation
channels. One reason for this may be that many Cl− channels perform functions that might …

This article reviews the current state of knowledge about the bestrophins, a newly identified
family of proteins that can function both as Cl− channels and as regulators of voltage-gated …

In recent decades, growing scientific evidence supports the role of ion channels in the
development of different cancers. Both potassium selective pores and chloride …

Activation of an apical Ca 2+-dependent Cl− channel (CaCC) is the rate-limiting step for fluid
secretion in many exocrine tissues. Here, we compared the properties of native CaCC in …

The volume‐regulated anion channel (VRAC) plays a pivotal role in cell volume regulation
in essentially all cell types studied. Additionally, VRAC appears to contribute importantly to a …

Maintenance of skeletal muscle is beneficial in obesity and Type 2 diabetes. Mechanical
stimulation can regulate skeletal muscle differentiation, growth and metabolism; however …

There are a number of mammalian anion channel types associated with cell volume
changes. These channel types are classified into two groups: volume-activated anion …