SARS-CoV-2 neutralizing antibodies for COVID-19 prevention and treatment

D Li, GD Sempowski, KO Saunders… - Annual review of …, 2022 - annualreviews.org
Prophylactic and therapeutic drugs are urgently needed to combat coronavirus disease
2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV …

Worse than the disease? Reviewing some possible unintended consequences of the mRNA vaccines against COVID-19

S Seneff, G Nigh - International Journal of Vaccine Theory, Practice, and …, 2021 - ijvtpr.com
Operation Warp Speed brought to market in the United States two mRNA vaccines,
produced by Pfizer and Moderna. Interim data suggested high efficacy for both of these …

Structure-guided multivalent nanobodies block SARS-CoV-2 infection and suppress mutational escape

PA Koenig, H Das, H Liu, BM Kümmerer, FN Gohr… - Science, 2021 - science.org
INTRODUCTION The global scale and rapid spread of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) pose unprecedented challenges to society, health care …

Two different antibody-dependent enhancement (ADE) risks for SARS-CoV-2 antibodies

DO Ricke - Frontiers in immunology, 2021 - frontiersin.org
COVID-19 (SARS-CoV-2) disease severity and stages varies from asymptomatic, mild flu-
like symptoms, moderate, severe, critical, and chronic disease. COVID-19 disease …

Waning antibody responses in COVID-19: what can we learn from the analysis of other coronaviruses?

A Hamady, JJ Lee, ZA Loboda - Infection, 2022 - Springer
Objectives The coronavirus disease 2019 (COVID-19), caused by the novel betacoronavirus
severe acute respiratory syndrome 2 (SARS-CoV-2), was declared a pandemic in March …

Antibody-dependent enhancement of SARS-CoV-2 infection is mediated by the IgG receptors FcγRIIA and FcγRIIIA but does not contribute to aberrant cytokine …

T Maemura, M Kuroda, T Armbrust, S Yamayoshi… - MBio, 2021 - Am Soc Microbiol
ABSTRACT The coronavirus disease 2019 (COVID-19) pandemic has raised concerns
about the detrimental effects of antibodies. Antibody-dependent enhancement (ADE) of …

Integrative overview of antibodies against SARS-CoV-2 and their possible applications in COVID-19 prophylaxis and treatment

NA Valdez-Cruz, E García-Hernández, C Espitia… - Microbial cell …, 2021 - Springer
SARS-CoV-2 is a novel β-coronavirus that caused the COVID-19 pandemic disease, which
spread rapidly, infecting more than 134 million people, and killing almost 2.9 million thus far …

Boosting of cross-reactive antibodies to endemic coronaviruses by SARS-CoV-2 infection but not vaccination with stabilized spike

AR Crowley, H Natarajan, AP Hederman, CA Bobak… - Elife, 2022 - elifesciences.org
Preexisting antibodies to endemic coronaviruses (CoV) that cross-react with SARS-CoV-2
have the potential to influence the antibody response to COVID-19 vaccination and infection …

[HTML][HTML] Antibody-Dependent Enhancement (ADE) and the role of complement system in disease pathogenesis

S Thomas, MK Smatti, A Ouhtit, FS Cyprian… - Molecular …, 2022 - Elsevier
Antibody-dependent enhancement (ADE) has been associated with severe disease
outcomes in several viral infections, including respiratory infections. In vitro and in vivo …

The investigation of mRNA vaccines formulated in liposomes administrated in multiple routes against SARS-CoV-2

H Huang, C Zhang, S Yang, W Xiao, Q Zheng… - Journal of Controlled …, 2021 - Elsevier
COVID-19 pandemic has resulted in an unprecedented global public health crisis. It is
obvious that SARS-CoV-2 vaccine is needed to control the global COVID-19 public health …