Human induced pluripotent stem cells (hiPSCs) are invaluable resources for producing high-
quality differentiated cells in unlimited quantities for both basic research and clinical use …

Osteoarthritis (OA) is a long-term, persistent joint disorder characterized by bone and
cartilage degradation, resulting in tightness, pain, and restricted movement. Current attempts …

The repair of damaged articular cartilage using currently available implantation techniques
is not sufficient for the full recovery of patients. Pluripotent stem cells (iPSC)-based therapies …

Polyether ionophore salinomycin (SAL) and its semi-synthetic derivatives are recognized as
very promising anticancer drug candidates due to their activity against various types of …

Cartilage tissue, characterized by its limited regenerative capacity, presents significant
challenges in clinical therapy. Recent advancements in cartilage regeneration have focused …

Human induced pluripotent stem cells (hiPSCs) can be differentiated into chondrocyte-like
cells. However, implantation of these cells is not without risk given that those transplanted …

Introduction: Repairing damaged cartilage poses significant challenges, particularly in cases
of congenital cartilage defects such as microtia or congenital tracheal stenosis, or as a …

Quality control systems are critical to improving laboratory practices and contribute
significantly to success in human in vitro fertilisation (IVF). The mouse embryo assay (MEA) …

Secretome profiles of MSCs are reflective of their local microenvironments and able to
create an impact on the surrounding cells, eliciting regenerative responses that open up the …

Materials and Methods: CM was collected from Yazd2 (hESCs; 46, XY) derived MSCs
confluent cultures and stored at-20 C. Yazd4 hESC line (46, XX) was induced for …