MXene in the lens of biomedical engineering: synthesis, applications and future outlook

A Zamhuri, GP Lim, NL Ma, KS Tee… - Biomedical engineering …, 2021 - Springer
MXene is a recently emerged multifaceted two-dimensional (2D) material that is made up of
surface-modified carbide, providing its flexibility and variable composition. They consist of …

MXene-based aptasensors: Advances, challenges, and prospects

S Ullah, F Shahzad, B Qiu, X Fang, A Ammar… - Progress in Materials …, 2022 - Elsevier
The combination of 2D MXenes with high affinity aptamers has resulted in the development
of innovative aptasensing approaches for food/water safety and clinical diagnosis. Aptamers …

[HTML][HTML] Different responses to neoadjuvant chemotherapy in urothelial carcinoma molecular subtypes

G Sjödahl, J Abrahamsson, K Holmsten, C Bernardo… - European urology, 2022 - Elsevier
Background For muscle-invasive bladder cancer (MIBC), no tissue biomarkers are available
for clinical use to predict response to neoadjuvant chemotherapy. Objective To investigate …

Ti3C2Tx MXene and polyoxometalate nanohybrid embedded with polypyrrole: Ultra-sensitive platform for the detection of osteopontin

S Zhou, C Gu, Z Li, L Yang, L He, M Wang… - Applied Surface …, 2019 - Elsevier
A nanohybrid of Ti 3 C 2 T x MXene and phosphomolybdic acid (PMo 12) embedded with
polypyrrole (denoted as PPy@ Ti 3 C 2 T x/PMo 12) was synthesized and used as the boost …

The matrix revolution: matricellular proteins and restructuring of the cancer microenvironment

C Gerarduzzi, U Hartmann, A Leask, E Drobetsky - Cancer research, 2020 - AACR
The extracellular matrix (ECM) surrounding cells is indispensable for regulating their
behavior. The dynamics of ECM signaling are tightly controlled throughout growth and …

MXenes and MXene-based materials with cancer diagnostic applications: challenges and opportunities

G Jamalipour Soufi, P Iravani, A Hekmatnia… - Comments on …, 2022 - Taylor & Francis
MXenes and MXene-based materials exhibited unique properties such as remarkable
conductivity, hydrophilicity, high ion transport features, low diffusion barrier, biocompatibility …

Osteopontin in cancer: mechanisms and therapeutic targets

Y Kariya, Y Kariya - International Journal of Translational Medicine, 2022 - mdpi.com
Despite significant advances in the understanding of cancer biology, cancer is still a leading
cause of death worldwide. Expression of the tumor microenvironment component …

The intracellular and secreted sides of osteopontin and their putative physiopathological roles

ACSF Bastos, AVP Gomes, GR Silva… - International Journal of …, 2023 - mdpi.com
Classically, osteopontin (OPN) has been described as a secreted glycophosprotein. Indeed,
most data concerning its physiological and pathological roles are mainly related to the …

Osteopontin as a biomarker in chronic kidney disease

SK Sinha, M Mellody, MB Carpio, R Damoiseaux… - Biomedicines, 2023 - mdpi.com
Osteopontin (OPN) is a ubiquitously expressed protein with a wide range of physiological
functions, including roles in bone mineralization, immune regulation, and wound healing …

Vitamin D receptor mediates a myriad of biological actions dependent on its 1, 25‐dihydroxyvitamin D ligand: distinct regulatory themes revealed by induction of …

MR Haussler, S Livingston, ZL Sabir, CA Haussler… - JBMR …, 2021 - Wiley Online Library
The hormonal vitamin D metabolite, 1, 25‐dihydroxyvitamin D [1, 25 (OH) 2D], produced in
kidney, acts in numerous end organs via the nuclear vitamin D receptor (VDR) to trigger …