New approaches to improve a peptide vaccine against porcine Taenia solium cysticercosis

E Sciutto, G Fragoso, K Manoutcharian… - Archives of Medical …, 2002 - Elsevier
Cysticercosis caused by Taenia solium frequently affects human health and rustic
porciculture. Cysticerci may localize in the central nervous system of humans causing …

Progress towards development of a vaccine for amebiasis

SL Stanley Jr - Clinical Microbiology Reviews, 1997 - Am Soc Microbiol
The application of molecular biologic techniques over the past decade has seen a
tremendous growth in our knowledge of the biology of Entamoeba histolytica, the causative …

Expression systems and developments in plant‐made vaccines

MM Rigano, AM Walmsley - Immunology and cell biology, 2005 - Wiley Online Library
Delivery of vaccines to mucosal surfaces can elicit humoral and cell‐mediated responses of
the mucosal and systemic immune systems, evoke less pain and discomfort than parenteral …

Fusions to the cholera toxin B subunit: influence on pentamerization and GM1 binding

S Liljeqvist, S Ståhl, C Andréoni, H Binz… - Journal of …, 1997 - Elsevier
The cholera toxin B (CTB) subunit has been used extensively in vaccine research as a
carrier for peptide immunogens due to its immunopotentiating properties, where coupling …

Surface display of the cholera toxin B subunit on Staphylococcus xylosus and Staphylococcus carnosus

S Liljeqvist, P Samuelson, M Hansson… - Applied and …, 1997 - Am Soc Microbiol
The heterologous surface expression of the cholera toxin B subunit (CTB) from Vibro
cholerae in two staphylococcal species, Staphylococcus xylosus and Staphylococcus …

The Salmonella ompC gene: structure and use as a carrier for heterologous sequences

JL Puente, D Juárez, M Bobadilla, CF Arias, E Calva - Gene, 1995 - Elsevier
The Salmonella typhi (St) ompC gene codes for a major outer membrane protein (OMP) that
is highly expressed in both low and high osmolarity. By hybridization studies with the entire …

Rabies glycoprotein fused with B subunit of cholera toxin expressed in tobacco plants folds into biologically active pentameric protein

S Roy, A Tyagi, S Tiwari, A Singh, SV Sawant… - Protein expression and …, 2010 - Elsevier
The pentameric B subunit of cholera toxin (CtxB) is an efficient mucosal adjuvant for
vaccines. We report the expression of a chimeric protein comprising the synthetic cholera …

[HTML][HTML] Structure-guided design and immunological characterization of immunogens presenting the HIV-1 gp120 V3 loop on a CTB scaffold

M Totrov, X Jiang, XP Kong, S Cohen, C Krachmarov… - Virology, 2010 - Elsevier
V3 loop is a major neutralizing determinant of the HIV-1 gp120. Using 3D structures of
cholera toxin B subunit (CTB), complete V3 in the gp120 context, and V3 bound to a …

Targeting of plant-derived vaccine antigens to immunoresponsive mucosal sites

MM Rigano, F Sala, CJ Arntzen, AM Walmsley - Vaccine, 2003 - Elsevier
Most pathogenic microorganisms enter their host via the mucosal surfaces lining the
digestive, respiratory and urino-reproductive tracts of the body. The most efficient means of …

Oral immunization with the dodecapeptide repeat of the serine-rich Entamoeba histolytica protein (SREHP) fused to the cholera toxin B subunit induces a mucosal and …

T Zhang, E Li, SL Stanley Jr - Infection and immunity, 1995 - Am Soc Microbiol
The intestinal protozoan parasite Entamoeba histolytica causes amebic dysentery, a major
cause of morbidity worldwide. The induction of a mucosal antibody response capable of …