Reactive oxygen species (ROS) are a chemically defined group of reactive molecules
derived from molecular oxygen. ROS are involved in a plethora of processes in cells in all …

Insect guts present distinctive environments for microbial colonization, and bacteria in the
gut potentially provide many beneficial services to their hosts. Insects display a wide range …

Reactive oxygen species (ROS) are a chemical class of molecules that have generally been
conceptualized as deleterious entities, albeit ones whose destructive properties could be …

To combat infection, the fruit fly Drosophila melanogaster relies on multiple innate defense
reactions, many of which are shared with higher organisms. These reactions include the use …

Most, if not all, animals coexist with a complement of prokaryotic symbionts that confer a
variety of physiologic benefits. In humans, the interaction between animal and bacterial cells …

There is growing interest in using Drosophila melanogaster to elucidate mechanisms that
underlie the complex relationships between a host and its microbiota. In addition to the …

The digestive tract plays a central role in the digestion and absorption of nutrients. Far from
being a passive tube, it provides the first line of defense against pathogens and maintains …

The resident prokaryotic microbiota of the metazoan gut elicits profound effects on the
growth and development of the intestine. However, the molecular mechanisms of symbiotic …

Cells in intestinal epithelia turn over rapidly due to damage from digestion and toxins
produced by the enteric microbiota. Gut homeostasis is maintained by intestinal stem cells …

Gut homeostasis is controlled by both immune and developmental mechanisms, and its
disruption can lead to inflammatory disorders or cancerous lesions of the intestine. While the …