Differential microglial morphological response, TNFα, and viral load in sedentary-like and active murine models after systemic non-neurotropic dengue virus infection

GF Gomes, RDF Peixoto, BG Maciel… - … of Histochemistry & …, 2019 - journals.sagepub.com
Peripheral inflammatory stimuli increase proinflammatory cytokines in the bloodstream and
central nervous system and activate microglial cells. Here we tested the hypothesis that …

Callithrix penicillata: a feasible experimental model for dengue virus infection

MS Ferreira, PHG de Castro, GA Silva, SMM Casseb… - Immunology …, 2014 - Elsevier
Although the murine models have the feasibility to reproduce some signs of dengue Virus
(DENV) infection, the use of isogenic hosts with polarized immune response patterns does …

Antibody‐enhanced dengue disease generates a marked CNS inflammatory response in the black‐tufted marmoset Callithrix penicillata

BCB Vasconcelos, JA Vieira, GO Silva… - …, 2016 - Wiley Online Library
Severe dengue disease is often associated with long‐term neurological impairments, but it
is unclear what mechanisms are associated with neurological sequelae. Previously, we …

[HTML][HTML] Hierarchical cluster analysis of three-dimensional reconstructions of unbiased sampled microglia shows not continuous morphological changes from stage 1 …

DG Diniz, GO Silva, TB Naves, TN Fernandes… - Frontiers in …, 2016 - frontiersin.org
It is known that microglial morphology and function are related, but few studies have
explored the subtleties of microglial morphological changes in response to specific …

[HTML][HTML] Limbic encephalitis brain damage induced by cocal virus in adult mice is reduced by environmental enrichment: neuropathological and behavioral studies

PSL Freitas, AVL Lima, KGB Carvalho, TS Cabral… - Viruses, 2020 - mdpi.com
We previously demonstrated, using the Piry virus model, that environmental enrichment
promotes higher T-cell infiltration, fewer microglial changes, and faster central nervous …

Aging and environmental enrichment exacerbate inflammatory response on antibody-enhanced dengue disease in immunocompetent murine model

DG Diniz, CAR Foro, MCK Sosthenes… - European Journal …, 2013 - journals.sagepub.com
We previously demonstrated in young mice that in comparison with animals raised in an
impoverished environment (IE), animals from an enriched environment (EE) show more …

Dengue Virus and the Relationship with MicroRNAs

S Casseb, K de Melo - Dengue Fever in a One Health …, 2020 - books.google.com
Dengue is an acute febrile disease caused by a virus of the genus Flavivirus, family
Flaviviridae, endemic in tropical regions of the globe. The agent is a virus with single …

[PDF][PDF] Limbic Encephalitis Brain Damage Induced by Cocal Virus in Adult Mice Is Reduced by Environmental Enrichment: Neuropathological and Behavioral Studies …

PSL Freitas, AVL Lima, KGB Carvalho, TS Cabral… - 2020 - pdfs.semanticscholar.org
We previously demonstrated, using the Piry virus model, that environmental enrichment
promotes higher T-cell infiltration, fewer microglial changes, and faster central nervous …

Alterações da morfologia da micróglia do septo lateral e comportamento semelhante ao ansioso em um modelo murino de inoculação sequencial de VDEN1 e …

GF GOMES - 2016 - repositorio.ufpa.br
RESUMO A infecção por dengue é a maior causa de mortes por infecções por arbovírus no
Brasil. A despeito de sua importância epidemiológica e um século de estudos sistemáticos …

[PDF][PDF] Aging and environmental enrichments exacerbate inflammatory response on antibody-enhanced dengue disease in immunocompetent murine model

B Barreto, A Hemorrágicas - researchgate.net
We previously demonstrated in young mice that in comparison with animals raised in an
impoverished environment (IE), animals from an enriched environment (EE) show more …