Therapeutic properties and pharmacological activities of asiaticoside and madecassoside: A review

S Bandopadhyay, S Mandal, M Ghorai… - Journal of Cellular …, 2023 - Wiley Online Library
Centella asiatica is an ethnomedicinal herbaceous species that grows abundantly in tropical
and sub‐tropical regions of China, India, South‐Eastern Asia and Africa. It is a popular …

Promising natural products in new drug design, development, and therapy for skin disorders: An overview of scientific evidence and understanding their mechanism of …

NA Mohd Zaid, M Sekar, SR Bonam… - Drug design …, 2023 - Taylor & Francis
The skin is the largest organ in the human body, composed of the epidermis and the dermis.
It provides protection and acts as a barrier against external menaces like allergens …

Bioactive wound dressing based on decellularized tendon and GelMA with incorporation of PDA-loaded asiaticoside nanoparticles for scarless wound healing

S Liu, Y Zhao, M Li, L Nie, Q Wei, OV Okoro… - Chemical Engineering …, 2023 - Elsevier
In this study, bioactive composite hydrogels were created using the decellularized
extracellular matrix (ECM), GelMA, and Polydopamine-loaded Asiaticoside (AC@ PDA) …

Keloid: genetic susceptibility and contributions of genetics and epigenetics to its pathogenesis

S Liu, H Yang, J Song, Y Zhang… - Experimental …, 2022 - Wiley Online Library
Keloid, characterized by fibroproliferative disorders of the skin, can be developed in people
of different genders, ages and ethnicities. Keloid can appear in any part of the body but are …

Tetracyclic and pentacyclic triterpenes with high therapeutic efficiency in wound healing approaches

R Ghiulai, OJ Roşca, DS Antal, M Mioc, A Mioc… - Molecules, 2020 - mdpi.com
Wounds are among the most common skin conditions, displaying a large etiological diversity
and being characterized by different degrees of severity. Wound healing is a complex …

Long non-coding RNA HOXA11-AS accelerates the progression of keloid formation via miR-124-3p/TGFβR1 axis

J Jin, ZH Jia, XH Luo, HF Zhai - Cell Cycle, 2020 - Taylor & Francis
Emerging evidence reveals the importance of long non-coding RNAs (lncRNAs) in the
development and progression of keloid formation, whereas the underlying mechanisms are …

Pinocembrin ameliorates skin fibrosis via inhibiting TGF-β1 signaling pathway

X Li, Y Zhai, B Xi, W Ma, J Zhang, X Ma, Y Miao, Y Zhao… - Biomolecules, 2021 - mdpi.com
Skin fibrotic diseases, such as keloids, are mainly caused by pathologic scarring of wounds
during healing and characterized by benign cutaneous overgrowths of dermal fibroblasts …

Enhanced in vitro efficacy for inhibiting hypertrophic scar by bleomycin-loaded dissolving hyaluronic acid microneedles

Y Xie, H Wang, J Mao, Y Li, M Hussain, J Zhu… - Journal of Materials …, 2019 - pubs.rsc.org
Hypertrophic scarring is a widespread skin disorder that affects a patient's confidence and
quality of life. Intralesional injection of bleomycin is one of the most commonly employed …

Insights into How Plant-Derived Extracts and Compounds Can Help in the Prevention and Treatment of Keloid Disease: Established and Emerging Therapeutic …

YC Boo - International Journal of Molecular Sciences, 2024 - mdpi.com
Keloid is a disease in which fibroblasts abnormally proliferate and synthesize excessive
amounts of extracellular matrix, including collagen and fibronectin, during the healing …

[HTML][HTML] MiR-203 regulates keloid fibroblast proliferation, invasion, and extracellular matrix expression by targeting EGR1 and FGF2

K Shi, X Qiu, W Zheng, D Yan, W Peng - Biomedicine & Pharmacotherapy, 2018 - Elsevier
Keloid is a fibrous benign tumor of the skin caused by increased fibroblast proliferation and
overproduction of extracellular matrix (ECM) in the dermis. Several miRNAs exhibit critical …