Nuclear mitochondrial DNA (mtDNA) segments (NUMTs) were discovered shortly after
sequencing the first human mitochondrial genome. They have earlier been considered to …

An essential element of compliance with ethical standards in scientific research is the
reporting of a verifiable declaration of ethical approval and, when human subjects are …

Nuclear mitochondrial DNA segments (NUMTs) are generated via transfer of portions of the
mitochondrial genome into the nuclear genome. Given their common origin, there is the …

Genetic associations between human mitochondrial DNA (mtDNA) heteroplasmy and
mitochondrial diseases, aging, and cancer have been elaborated, contributing a lot to the …

Motivation Assays in mitochondrial genomics rely on accurate read mapping and variant
calling. However, there are known and unknown nuclear paralogs that have fundamentally …

Nuclear mitochondrial pseudogenes (numts) may hinder the reconstruction of mtDNA
genomes and affect the reliability of mtDNA datasets for phylogenetic and population …

Despite a multitude of methods for the sample preparation, sequencing, and data analysis of
mitochondrial DNA (mtDNA), the demand for innovation remains, particularly in comparison …

Mitochondrial (mt) DNA sequence analysis is useful for assessing ancestral origin and
migration, identifying human remains, and examining evidentiary material in forensic …

Unique molecular identifiers (UMIs) are a promising approach to contend with errors
generated during PCR and massively parallel sequencing (MPS). With UMI technology …

In forensics, genetic human identification is generally achieved by nuclear STR DNA typing.
However, forensic samples often yield DNA in exiguous quantity and low quality, impairing …