HOX genes encode an evolutionarily conserved set of transcription factors that control how
the phenotype of an organism becomes organized during development based on its genetic …

Hox genes are an evolutionary highly conserved gene family. They determine the anterior-
posterior body axis in bilateral organisms and influence the developmental fate of cells …

A widely shared view reads that mesenchymal stem/stromal cells (" MSCs") are ubiquitous in
human connective tissues, can be defined by a common in vitro phenotype, share a …

Mesenchymal stromal cells nowadays emerge as a major player in the field of regenerative
medicine and translational research. They constitute, with their derived products, the most …

Hox genes encode evolutionarily conserved transcription factors that control skeletal
patterning in the developing embryo. They are expressed in regionally restricted domains …

In embryonic models and stem cell systems, mesenchymal cells derived from the
neuroectoderm can be distinguished from mesoderm-derived cells by their Hox-negative …

Stem cell therapy is a potential treatment for spinal cord injury and different stem cell types
have been grafted into animal models and humans suffering from spinal trauma. Due to …

Resident stem/progenitor cells in the lung are important for tissue homeostasis and repair.
However, a progenitor population for alveolar type II (ATII) cells in adult human lungs has …

Background MicroRNAs are a population of short non-coding RNAs with widespread
negative regulatory impact on mRNA translation. Unrestricted somatic stem cells (USSC) are …

The continuous discovery of human mesenchymal stem cells (hMSCs) in different tissues is
stirring up a tremendous interest as a cell source for regenerative medicine therapies …