Therapeutic effects of classic serotonergic psychedelics: A systematic review of modern‐era clinical studies

KAA Andersen, R Carhart‐Harris… - Acta Psychiatrica …, 2021 - Wiley Online Library
Objective To conduct a systematic review of modern‐era (post‐millennium) clinical studies
assessing the therapeutic effects of serotonergic psychedelics drugs for mental health …

Mechanisms and molecular targets surrounding the potential therapeutic effects of psychedelics

AM Jaster, J González-Maeso - Molecular psychiatry, 2023 - nature.com
Psychedelics, also known as classical hallucinogens, have been investigated for decades
due to their potential therapeutic effects in the treatment of neuropsychiatric and substance …

Psychedelics promote neuroplasticity through the activation of intracellular 5-HT2A receptors

MV Vargas, LE Dunlap, C Dong, SJ Carter, RJ Tombari… - Science, 2023 - science.org
Decreased dendritic spine density in the cortex is a hallmark of several neuropsychiatric
diseases, and the ability to promote cortical neuron growth has been hypothesized to …

Pivotal mental states

A Brouwer, RL Carhart-Harris - Journal of …, 2021 - journals.sagepub.com
This paper introduces a new construct, the 'pivotal mental state', which is defined as a hyper-
plastic state aiding rapid and deep learning that can mediate psychological transformation …

The corticotropin-releasing factor family: physiology of the stress response

JM Deussing, A Chen - Physiological reviews, 2018 - journals.physiology.org
The physiological stress response is responsible for the maintenance of homeostasis in the
presence of real or perceived challenges. In this function, the brain activates adaptive …

The hypothalamic-pituitary-adrenal axis in PTSD: Pathophysiology and treatment interventions

BW Dunlop, A Wong - Progress in Neuro-psychopharmacology and …, 2019 - Elsevier
Questions of how altered functioning of the hypothalamic pituitary adrenal (HPA) axis
contribute to the development and maintenance of posttraumatic stress disorder (PTSD) …

The neurobiology of psychedelic drugs: implications for the treatment of mood disorders

FX Vollenweider, M Kometer - Nature Reviews Neuroscience, 2010 - nature.com
After a pause of nearly 40 years in research into the effects of psychedelic drugs, recent
advances in our understanding of the neurobiology of psychedelics, such as lysergic acid …

Region-specific roles of the corticotropin-releasing factor–urocortin system in stress

MJAG Henckens, JM Deussing, A Chen - Nature Reviews …, 2016 - nature.com
Dysregulation of the corticotropin-releasing factor (CRF)–urocortin (UCN) system has been
implicated in stress-related psychopathologies such as depression and anxiety. It has been …

Relationships among smartphone addiction, anxiety, and family relations

NS Hawi, M Samaha - Behaviour & Information Technology, 2017 - Taylor & Francis
Smartphones have become ubiquitous in people's lives to an extent that necessitates the
investigation of their negative impact. The scarcity of such investigations triggered our …

LSD-stimulated behaviors in mice require β-arrestin 2 but not β-arrestin 1

RM Rodriguiz, V Nadkarni, CR Means, VM Pogorelov… - Scientific reports, 2021 - nature.com
Recent evidence suggests that psychedelic drugs can exert beneficial effects on anxiety,
depression, and ethanol and nicotine abuse in humans. However, their hallucinogenic side …