Indole is a versatile pharmacophore, a privileged scaffold and an outstanding heterocyclic
compound with wide ranges of pharmacological activities due to different mechanisms of …

Cancer, which is the uncontrolled growth of cells, is the second leading cause of death after
heart disease. Targeting drugs, especially to specific genes and proteins involved in growth …

The increasing incidence of antibiotic resistance has forced the development of unique
antimicrobials with novel multitargeting mechanisms to combat infectious diseases caused …

Antibacterial-resistance speaks to an overall alarm, particularly in regards to the flare-up of
methicillin-resistance Staphylococcus aureus (MRSA), a classic reason for genuine skin and …

Due to the structure of acylhydrazones both by the pharmacophore–CO–NH–N= group and
by the different substituents present in the molecules of compounds of this class, various …

In the present scenario, there has been a lot of consideration toward the field of free radical
chemistry. Free radicals responsive oxygen species are produced by different endogenous …

The emergence of pathogenic and drug-resistant microorganisms seriously threatens public
safety. This work constructed a unique type of thiazolyl hydrazineylidenyl indolones (THIs) to …

4-Phenyl-3-[2-(phenylamino) ethyl]-1 H-1, 2, 4-triazole-5 (4 H)-thione was used as a starting
compound for the synthesis of the corresponding 1, 2, 4-triazol-3-ylthioacetohydrazide …

In the current research work novel bis‐Schiff base products of benzyl phenyl ketone nucleus
were synthesized via two step reactions in excellent yields. Using FTIR, EI‐MS and 1H‐NMR …

Indole chalcones were designed and synthesized as a promising set of compounds against
H 37 Rv strain of Mycobacterium tuberculosis. Within this library of compounds,(E)-1-(furan …