Chagas disease is currently endemic to 21 Latin-American countries and has also become a
global concern because of globalization and mass migration of chronically infected …

American trypanosomiasis (Chagas' disease) can be transmitted by blood transfusion. For
almost 40 years, this transmission has been limited to Latin America, but recently, three …

The cysteine proteases, cruzain and Tbr CATL (rhodesain), are therapeutic targets for
Chagas disease and Human African Trypanosomiasis, respectively. Among the known …

Results of our studies on the reactivity of chagasic and leishmaniasic sera with the purified
T. cruzi‐specific antigen 163B6, as assessed by ELISA, and with complex antigenic mixtures …

The aims of this study were to characterize human American tegumentary leishmaniasis,
which includes cutaneous, mucocutaneous and mucosal leishmaniasis, in Northwest …

To stimulate both local and systemic immune responses against Trypanosoma cruzi,
Salmonella enterica serovar Typhimurium aroA was exploited as a DNA delivery system for …

In a study, carried out in 2000, of the clinical and parasitological status of a Wichi Aboriginal
community living in the suburbs of Tartagal, northern Salta, Argentina, 154 individuals were …

Some Leishmania species affect humans in two principal forms: visceral and cutaneous
leishmaniosis (CL). Several studies have identified dogs as the main reservoirs of the …

The crucial role played by Ag163B6/cruzipain, the major cystein proteinase of Trypanosoma
cruzi, in the process of parasite internalization into mammalian cells and IgG hydrolysis …

This chapter focuses on trypanosomal cysteine peptidases (CPs), especially cruzain, from
Trypanosoma cruzi, and rhodesain and TbCatB, from Trypanosoma brucei, describing their …