Nanoscale MOFs: From synthesis to drug delivery and theranostics applications

M Ding, W Liu, R Gref - Advanced Drug Delivery Reviews, 2022 - Elsevier
Since the first report in 1989, Metal-Organic Frameworks (MOFs) self-assembled from metal
ions or clusters, as well as organic linkers, have attracted extensive attention. Due to their …

Recent advances in cell membrane coated metal–organic frameworks (MOFs) for tumor therapy

W Liu, Q Yan, C Xia, X Wang, A Kumar… - Journal of Materials …, 2021 - pubs.rsc.org
In improving the tumor-targeting ability of metal–organic frameworks (MOFs) for tumor
therapy and avoiding the clearance as well as capture by the immune system, there are still …

A Novel Photosynthetic Biohybrid System for Microenvironment Regulation of Diabetes Retinopathy through Continuous Oxygen Supply and Nanozyme Cascade …

L Zhou, K Lan, X Huang, Y Huang, Y Jin… - Advanced Functional …, 2023 - Wiley Online Library
Abstract According to International Diabetes Federation Diabetes Atlas statistics, diabetic
retinopathy (DR) is the leading cause of vision loss in blinding diseases. The underlying …

Advances of nanomedicines in breast cancer metastasis treatment targeting different metastatic stages

W Yu, C Hu, H Gao - Advanced Drug Delivery Reviews, 2021 - Elsevier
Breast cancer is the most common tumor in women, and the metastasis further increases the
malignancy with extremely high mortality. However, there is almost no effective method in …

Recent advances in nanoplatform construction strategy for alleviating tumor hypoxia

J Shen, G Chen, L Zhao, G Huang, H Liu… - Advanced …, 2023 - Wiley Online Library
Hypoxia is a typical feature of most solid tumors and has important effects on tumor cells'
proliferation, invasion, and metastasis. This is the key factor that leads to poor efficacy of …

Red blood cell-mimic nanocatalyst triggering radical storm to augment cancer immunotherapy

J Li, S Wang, X Lin, Y Cao, Z Cai, J Wang, Z Zhang… - Nano-Micro Letters, 2022 - Springer
Red blood cells (RBCs) have recently emerged as promosing candidates for cancer
treatment in terms of relieving tumor hypoxia and inducing oxidative damage against cancer …

[HTML][HTML] Self-propelled nanomotor reconstructs tumor microenvironment through synergistic hypoxia alleviation and glycolysis inhibition for promoted anti-metastasis

W Yu, R Lin, X He, X Yang, H Zhang, C Hu… - … Pharmaceutica Sinica B, 2021 - Elsevier
Solid tumors always exhibit local hypoxia, resulting in the high metastasis and inertness to
chemotherapy. Reconstruction of hypoxic tumor microenvironment (TME) is considered a …

Research progress in oxygen carrier design and application

Q Ye, D Zheng, K Chen, J Wu - Molecular Pharmaceutics, 2023 - ACS Publications
Ischemia or hypoxia can lead to pathological changes in the metabolism and function of
tissues and then lead to various diseases. Timely and effective blood resuscitation or …

Red blood cell inspired strategies for drug delivery: emerging concepts and new advances

E Zhang, P Phan, HA Algarni, Z Zhao - Pharmaceutical Research, 2022 - Springer
In the past five decades, red blood cells (RBCs) have been extensively explored as drug
delivery systems due to their distinguishing potential in modulating the pharmacokinetic …

[HTML][HTML] A novel PEG-mediated approach to entrap hemoglobin (Hb) within ZIF-8 nanoparticles: Balancing crystalline structure, Hb content and functionality

C Coll-Satue, M Rubio-Huertas, A Ducrot… - Biomaterials …, 2024 - Elsevier
Hemoglobin (Hb)-based oxygen carriers are investigated as a potential alternative or
supplement to regular blood transfusions, particularly in critical and life-threatening …