Nanoparticle-mediated pulmonary drug delivery: a review

M Paranjpe, CC Müller-Goymann - International journal of molecular …, 2014 - mdpi.com
Colloidal drug delivery systems have been extensively investigated as drug carriers for the
application of different drugs via different routes of administration. Systems, such as solid …

Phage therapy of pulmonary infections

ST Abedon - Bacteriophage, 2015 - Taylor & Francis
It is generally agreed that a bacteriophage-associated phenomenon was first
unambiguously observed one-hundred years ago with the findings of Twort in 1915. This …

Rifampicin loaded chitosan nanoparticle dry powder presents an improved therapeutic approach for alveolar tuberculosis

T Rawal, R Parmar, RK Tyagi, S Butani - Colloids and Surfaces B …, 2017 - Elsevier
Current treatment therapeutic approach for tuberculosis is the administration of first line
drugs in the form of tablets and capsules for 4–6 months. However, this approach leads to …

Chitosan nanoparticles as a promising approach for pulmonary delivery of bedaquiline

T Rawal, S Patel, S Butani - European Journal of Pharmaceutical Sciences, 2018 - Elsevier
The purpose of the present research work was to explore chitosan nanoparticles (NPs) of a
novel anti-tubercular drug, bedaquiline (BDQ) in order to reduce dose and side effects …

Tuberculosis and its treatment: an overview

R Bansal, D Sharma, R Singh - Mini reviews in medicinal …, 2018 - ingentaconnect.com
Tuberculosis (TB) is a primordial infectious disease that mainly affects the lungs. M.
tuberculosis (Mycobacterium tuberculosis) is the etiological agent of TB and currently more …

The influence of surface active l-leucine and 1, 2-dipalmitoyl-sn-glycero-3-phosphatidylcholine (DPPC) in the improvement of aerosolization of pyrazinamide and …

BB Eedara, B Rangnekar, C Doyle, A Cavallaro… - International journal of …, 2018 - Elsevier
Pharmacotherapy of tuberculosis is potentially more efficient when delivered by the inhaled
route than by the current oral and/or parenteral routes due to the higher concentration of …

Bedaquiline containing triple combination powder for inhalation to treat drug-resistant tuberculosis

B Rangnekar, MAM Momin, BB Eedara, S Sinha… - International journal of …, 2019 - Elsevier
Drug-resistant tuberculosis (DR-TB) is an emerging health problem, challenging the
effective control of global TB. Current treatment of DR-TB includes administration of multiple …

Inhaled dry powder formulations for treating tuberculosis

S Das, I Tucker, P Stewart - Current Drug Delivery, 2015 - ingentaconnect.com
Tuberculosis is the second leading cause of death from infectious diseases. Although
antitubercular drugs have been traditionally administered orally, there is a growing interest …

Respiratory tract deposition and distribution pattern of microparticles in mice using different pulmonary delivery techniques

NK Kunda, DN Price, P Muttil - Vaccines, 2018 - mdpi.com
Pulmonary delivery of drugs and vaccines is an established route of administration, with
particulate-based carriers becoming an attractive strategy to enhance the benefits of …

The long and winding road to inhaled TB therapy: Not only the bug's fault

S Giovagnoli, A Schoubben, M Ricci - Drug development and …, 2017 - Taylor & Francis
Not all of the issues impacting the success of tuberculosis (TB) treatment arise from
pathogen-related disease characteristics. Nowadays, there is an increasing awareness that …