Rapid, accurate, sputum-free tests for tuberculosis (TB) triage and confirmation are urgently
needed to close the widening diagnostic gap. We summarise key technologies and review …

Background Sputum is the most widely used sample to diagnose active tuberculosis, but
many people living with HIV are unable to produce sputum. Urine, in contrast, is readily …

Despite multiple advances in tuberculosis (TB), there is still a lack of effective methods
available for its diagnosis. To this end, we developed a novel nanozyme-mediated …

In childhood tuberculosis (TB), with an estimated 69% of missed cases in children under 5
years of age, the case detection gap is larger than in other age groups, mainly due to its …

New tuberculosis (TB) diagnostics are at a crossroads: their development, evaluation, and
implementation is severely damaged by resource diversion due to COVID-19. Yet several …

Background Diagnosis of tuberculosis (TB) is still difficult. The purpose of our study was to
evaluate the diagnostic accuracy of Mycobacterium tuberculosis cell-free DNA (cfDNA) for …

The recognition that drug-resistant tuberculosis (DR-TB) poses a major threat to global
tuberculosis (TB) control efforts has catalysed the development of new and urgently needed …

Introduction Female genital tuberculosis (TB) is a common form of extrapulmonary TB
(EPTB) with varied clinical presentations, ie. infertility, pelvic pain, and menstrual …

Background Despite expanded access to antiretroviral therapy (ART) and the rollout of the
World Health Organization's (WHO)'test‐and‐treat'strategy, the proportion of people with HIV …

Quantitative nucleic acid amplification testing (NAAT) is a key enabling technology for
infectious disease management, especially in instances where viral load informs therapeutic …