Role of lymphocytes, macrophages and immune receptors in suppression of tumor immunity

A Singh, V Anang, K Kumari, SK Kottarath… - Progress in Molecular …, 2023 - Elsevier
Cancer is now the leading cause of mortality across the world. Inflammatory immune cells
are functionally important in the genesis and progression of tumors, as demonstrated by …

Receptors of immune cells mediates recognition for tumors

V Anang, A Singh, SK Kottarath, C Verma - Progress in Molecular Biology …, 2023 - Elsevier
Over the last few decades, the immune system has been steered toward eradication of
cancer cells with the help of cancer immunotherapy. T cells, B cells, monocytes …

[HTML][HTML] HSP-27 and HSP-70 negatively regulate protective defence responses from macrophages during mycobacterial infection

SSK Saraswati, AK Rana, A Singh, V Anang… - Microbes and …, 2023 - Elsevier
Mycobacterium tuberculosis attenuates many defence responses from alveolar
macrophages to create a niche at sites of infection in the human lung. Levels of Heat Shock …

Potassium ion channel Kir2.1 negatively regulates protective responses to Mycobacterium bovis BCG

V Sinha, A Singh, A Singh… - Journal of Leukocyte …, 2024 - academic.oup.com
Tuberculosis caused by the pathogen Mycobacterium tuberculosis leads to increased
mortality and morbidity worldwide. The prevalence of highly drug-resistant strains has …

Butyrate induces oxidative burst mediated apoptosis via Glucose-6-Phosphate Dehydrogenase (G6PDH) in macrophages during mycobacterial infection

AK Rana, SSK Saraswati, V Anang, A Singh… - Microbes and …, 2024 - Elsevier
Microorganisms present in the gut modulate host defence responses against infections in
order to maintain immune homeostasis. This host-microbe crosstalk is regulated by gut …

Suppressive effects of toll-like receptor 2, toll-like receptor 4, and toll-like receptor 7 on protective responses to Mycobacterium bovis BCG from epithelial cells

A Singh, A Singh, SSK Saraswati, AK Rana… - Microbes and …, 2024 - Elsevier
Mycobacteria have several mechanisms for evasion of protective responses mounted by the
host. In this study, we unravel yet another mechanism that is mediated by Toll-Like …