The circadian clock and sleep are essential for human physiology and behavior;
deregulation of circadian rhythms impairs health and performance. Circadian clocks and …

In this report, sex/gender research relevant to reproduction on Earth, in conjunction with the
extant human and animal observations in space, was used to identify knowledge gaps and …

Dry immersion (DI) is a Russian-developed, ground-based model to study the physiological
effects of microgravity. It accurately reproduces environmental conditions of weightlessness …

Environmental factors in space are dramatically different from those on Earth. The
spaceflight environment has been known to influence human physiology and behavior on …

Most organisms on Earth possess circadian rhythms in their physiology and behaviors that
allow them to resonate with the cycling environment over a 24‐h period. However, in human …

Twenty-four-hour rhythms in physiology and behaviour are shaped by circadian clocks,
environmental rhythms, and feedback of behavioural rhythms onto physiology. In space, 24 …

Despite the development and great progress in the field of space biology, the astronauts are
still facing many challenges in space. The space environment in which astronauts stay …

Opioid therapy must be adjusted to the rhythm of a cancer patient's pain to ensure adequate
symptom control at the end of life (EOL). However, to-date no study has explored the rhythm …

Purpose Prolonged weightlessness exposure generates cardiovascular deconditioning, with
potential implications on ECG circadian rhythms. Head-down (− 6°) tilt (HDT) bed rest is a …

The circadian clock plays a critical role in synchronizing the inner molecular, metabolic and
physiological processes to environmental cues that cycle with a period of 24 h. Non-24 h …