Underlying features of prostate cancer—statistics, risk factors, and emerging methods for its diagnosis

CV Berenguer, F Pereira, JS Câmara, JAM Pereira - Current Oncology, 2023 - mdpi.com
Prostate cancer (PCa) is the most frequently occurring type of malignant tumor and a leading
cause of oncological death in men. PCa is very heterogeneous in terms of grade …

Non-coding RNA-based therapeutics in cancer therapy: An emphasis on Wnt/β-catenin control

A Taheriazam, SD Bayanzadeh, MH Farahani… - European Journal of …, 2023 - Elsevier
Non-coding RNA transcripts are RNA molecules that have mainly regulatory functions and
they do not encode proteins. microRNAs (miRNAs), lncRNAs and circRNAs are major types …

[HTML][HTML] MALAT1 polymorphisms and lung cancer susceptibility in a Chinese northeast han population

G Tong, W Tong, R He, Z Cui, S Li… - International journal of …, 2022 - ncbi.nlm.nih.gov
Background: LncRNA MALAT1 (metastasis-associated lung adenocarcinoma transcript 1)
was competitive endogenous RNA (ceRNA) involved in various molecular processes for …

Importance of long non-coding RNAs in the pathogenesis, diagnosis, and treatment of prostate cancer

M Taheri, E Badrlou, BM Hussen, AH Kashi… - Frontiers in …, 2023 - frontiersin.org
Long non-coding RNAs (lncRNAs) are regulatory transcripts with essential roles in the
pathogenesis of almost all types of cancers, including prostate cancer. They can act as …

Variations in genomic regions encoding long non-coding RNA genes associated with increased prostate cancer risk

E Bozgeyik - Mutation Research/Reviews in Mutation Research, 2023 - Elsevier
From a single restriction fragment length polymorphism analysis to next generation
sequencing analysis that screens the entire human genome, testing for genomic variations …

[HTML][HTML] Impact of genetic variants of long noncoding RNA metastasis-associated lung adenocarcinoma transcript 1 on uterine cervical cancer

YH Sun, YH Chou, HY Tsai, YH Hsiao, CY Lee… - Journal of …, 2022 - ncbi.nlm.nih.gov
Genetic variants of long noncoding RNA metastasis-associated lung adenocarcinoma
transcript 1 (lncRNA MALAT1) have been reported to be associated with several cancers …

[HTML][HTML] Evaluation of the clinical significance of long non-coding RNA MALAT1 genetic variants in human lung adenocarcinoma

SH Lin, JW Lu, WT Hsieh, YE Chou, TC Su… - Aging (Albany …, 2024 - ncbi.nlm.nih.gov
Lung adenocarcinoma (LUAD) is the most frequent histological subtype of lung cancer,
which is the most common malignant tumor and the main cause of cancer-related mortality …

The Association between the NLRP3 Inflammasome and Specific Long-Non Coding RNAs (lncRNAs) in Cancer; New Perspective and Summary of Recent Studies

HO Alsaab, Y Almalki - Cell Biochemistry and Biophysics, 2024 - Springer
In response to cellular perturbations, a multimeric cytosolic protein complex known as the
NLRP3 inflammasome assembles. As a result of this assembly, caspase-1 is activated …

U1RNP/lncRNA/transcription cycle axis promotes tumorigenesis of hepatocellular carcinoma

S Li, S Zhang, M Huang, H Hu, Y Xie - Diagnostics, 2022 - mdpi.com
As a component of the spliceosome, U1 small nuclear ribonucleoproteins (U1RNPs) play
critical roles in RNA splicing, and recent studies have shown that U1RNPs could recruit long …

Genetic variants of LncRNAs HOTTIP and MEG3 influence nasopharyngeal carcinoma susceptibility and clinicopathologic characteristics in the Southern Chinese …

X Lao, Y Wang, R Huang, Y He, H Lu… - Infectious Agents and …, 2024 - Springer
Objective Recent studies have indicated that HOTTIP and MEG3 are associated with the
initiation and progression of various types of tumors, including nasopharyngeal carcinoma …