Transcriptome analysis of response mechanism to ammonia stress in Asian clam (Corbicula fluminea)

T Zhang, Z Yan, X Zheng, J Fan, S Wang, Y Wei… - Aquatic toxicology, 2019 - Elsevier
Corbicula fluminea is highly sensitive to ammonia, and its response mechanism to ammonia
stress is unclear. In this study, C. fluminea was exposed to different levels of ammonia …

Two distinct evolutionary conserved neural degeneration pathways characterized in a colonial chordate

C Anselmi, M Kowarsky, F Gasparini… - Proceedings of the …, 2022 - National Acad Sciences
Colonial tunicates are marine organisms that possess multiple brains simultaneously during
their colonial phase. While the cyclical processes of neurogenesis and neurodegeneration …

Expression dynamics of the aplysia abyssovirus

NS Kron, BW Neuman, S Kumar, PL Blackwelder… - Virology, 2024 - Elsevier
Two recent studies documented the genome of a novel, extremely large (35.9 kb), nidovirus
in RNA sequence databases from the marine neural model Aplysia californica. The goal of …

[HTML][HTML] Investigating the internal system of defense of Gastropoda Aplysia depilans (Gmelin, 1791): Focus on hemocytes

A Alesci, A Fumia, M Albano, E Messina… - Fish & Shellfish …, 2023 - Elsevier
The internal defense system of mollusks represents an efficient protection against
pathogens and parasites, involving several biological immune processes, such as …

High neural activity accelerates the decline of cognitive plasticity with age in Caenorhabditis elegans

Q Li, DC Marcu, O Palazzo, F Turner, D King… - Elife, 2020 - elifesciences.org
The ability to learn progressively declines with age. Neural hyperactivity has been
implicated in impairing cognitive plasticity with age, but the molecular mechanisms remain …

Animal models in neuroscience with alternative approaches: Evolutionary, biomedical, and ethical perspectives

S Neziri, AE Köseoğlu… - Animal Models and …, 2024 - Wiley Online Library
Animal models have been a crucial tool in neuroscience research for decades, providing
insights into the biomedical and evolutionary mechanisms of the nervous system, disease …

Transcriptome analysis provides genome annotation and expression profiles in the central nervous system of Lymnaea stagnalis at different ages

M Rosato, B Hoelscher, Z Lin, C Agwu, F Xu - BMC genomics, 2021 - Springer
Abstract Background The pond snail, Lymnaea stagnalis (L. stagnalis), has served as a
valuable model organism for neurobiology studies due to its simple and easily accessible …

Single‐neuron analysis of aging‐associated changes in learning reveals impairments in transcriptional plasticity

KK Badal, A Sadhu, BL Raveendra, C McCracken… - Aging cell, 2024 - Wiley Online Library
The molecular mechanisms underlying age‐related declines in learning and long‐term
memory are still not fully understood. To address this gap, our study focused on investigating …

SlugAtlas, a histological and 3D online resource of the land slugs Deroceras laeve and Ambigolimax valentianus

C Lozano-Flores, J Trujillo-Barrientos… - Plos one, 2024 - journals.plos.org
Due to their distinctive anatomical characteristics, land slugs are appealing research
subjects from a variety of angles, including stem cell biology, regeneration, embryonic …

Aplysia Neurons as a Model of Alzheimer's Disease: Shared Genes and Differential Expression

NS Kron, LA Fieber - Journal of Molecular Neuroscience, 2022 - Springer
Although Alzheimer's disease (AD) is the most common form of dementia in the United
States, development of therapeutics has proven difficult. Invertebrate alternatives to current …