Extracellular vesicles (EVs) represent a diverse class of lipid bilayer membrane vesicles
released by both animal and plant cells. These ubiquitous vesicles are involved in …

Abstract Background Extracellular vesicles (EVs) have been considered promising tools in
regenerative medicine. However, the nanoscale properties of EVs make them sensitive to …

Low-power sonication is widely used to disaggregate extracellular vesicles (EVs) after
isolation, however, the effects of sonication on EV samples beyond dispersion are unclear …

Wound healing is a dynamic process that involves a series of molecular and cellular events
aimed at replacing devitalized and missing cellular components and/or tissue layers …

Biobased therapy represents a promising strategy for myocardial repair. However, the
limitations of using live cells, including the risk of immunogenicity of allogeneic cells and …

The treatment of central nervous system (CNS) pathologies is severely hampered by the
presence of tightly regulated CNS barriers that restrict drug delivery to the brain. An …

Plant-derived extracellular vesicles (EVs) are capable of efficiency delivering mRNAs,
miRNAs, bioactive lipids, and proteins to mammalian cells. Plant-derived EVs critically …

Therapeutic extracellular vesicles (EVs) are in clinical trials and if successful, EVs wider use
will be largely affected by costs to patients/insurers and accessibility. EV preservation …

With significant advancement and development of extracellular vesicle (EV)-based
therapies, there is a growing need to understand how their storage affects their physical and …

Extracellular vesicles (EVs) are lipid vesicles secreted by all cells into the extracellular
space and act as nanosized biological messengers among cells. They carry a specific …