Osteoarthritis genetics has been transformed in the past decade through the application of
large-scale genome-wide association scans. So far, over 100 polymorphic DNA variants …

Objective In this review, we have highlighted the advances over the past year in genetics,
genomics and epigenetics in the field of osteoarthritis (OA). Methods A literature search of …

Abstract Purpose of Review Hand osteoarthritis (hand OA), the most common peripheral
arthritis in the world, is less studied than osteoarthritis (OA) of the knee and hip. However, it …

Osteoarthritis (OA) is the most common form of arthritis with well recognized multifactorial
nature. While several environmental factors such as older age, obesity and previous joint …

Osteoarthritis (OA) is increasingly recognised as a disease of diverse phenotypes with
variable clinical presentation, progression, and response to therapeutic intervention. This …

Osteoarthritis is the most prevalent whole-joint degenerative disorder, and is characterized
by the degradation of articular cartilage and the underlying bone structures. Almost 600 …

Background We investigated the effect of obesity on the association of genome-wide
associative studies (GWAS)-significant genes with the risk of knee osteoarthritis (KOA) …

Objective The osteoarthritis (OA)–associated single‐nucleotide polymorphism (SNP)
rs11583641 is located in COLGALT2, encoding a posttranslational modifier of collagen. In …

Purpose Hand osteoarthritis (OA) is a common cause of disability in older people. Although
often underemphasized, it may affect quality of life and imposes a considerable burden on …

This “year in review” provides a summary of the research findings on the topic of genetics,
genomics and epigenetics for osteoarthritis (OA) between Mar 2021–Apr 2022. A search …