Adjuvants are vaccine components that enhance the magnitude, breadth and durability of
the immune response. Following its introduction in the 1920s, alum remained the only …

Vaccinations are one of the most important preventive tools against infectious diseases.
Over time, many different types of vaccines have been developed concerning the antigen …

Modern subunit vaccines based on homogeneous antigens offer more precise targeting and
improved safety compared with traditional whole-pathogen vaccines. However, they are also …

In the present scenario, immunization is of utmost importance as it keeps us safe and
protects us from infectious agents. Despite the great success in the field of vaccinology …

After decades of slow progress, the last years have seen a rapid acceleration of the
development of adjuvanted vaccines which have lately been approved for human use …

Adjuvants are indispensable components of vaccines for stimulating optimal immune
responses to non-replicating, inactivated and subunit antigens. Eliciting balanced humoral …

Matrix-M™ adjuvant is a key component of several novel vaccine candidates. The Matrix-M
adjuvant consists of two distinct fractions of saponins purified from the Quillaja saponaria …

Traditional aluminum adjuvants can trigger strong humoral immunity but weak cellular
immunity, limiting their application in some vaccines. Currently, various immunomodulators …

Saponin adjuvants have been extensively studied for their use in veterinary and human
vaccines. Among them, QS-21 stands out owing to its unique profile of immunostimulating …

Over the last decades, vaccine development has advanced significantly in pursuing higher
safety with less side effects. However, this is often accompanied by a reduction in vaccine …