Phytostilbenes as agrochemicals: Biosynthesis, bioactivity, metabolic engineering and biotechnology

P Jeandet, A Vannozzi, E Sobarzo-Sánchez… - Natural product …, 2021 - pubs.rsc.org
Covering: 1976 to 2020. Although constituting a limited chemical family, phytostilbenes
represent an emblematic group of molecules among natural compounds. Ever since their …

Genetic approaches in improving biotechnological production of taxanes: An update

E Perez-Matas, D Hidalgo-Martinez, A Escrich… - Frontiers in Plant …, 2023 - frontiersin.org
Paclitaxel (PTX) and its derivatives are diterpene alkaloids widely used as
chemotherapeutic agents in the treatment of various types of cancer. Due to the scarcity of …

Production of highly bioactive resveratrol analogues pterostilbene and piceatannol in metabolically engineered grapevine cell cultures

A Martínez‐Márquez… - Plant biotechnology …, 2016 - Wiley Online Library
Grapevine stilbenes, particularly trans‐resveratrol, have a demonstrated pharmacological
activity. Other natural stilbenes derived from resveratrol such as pterostilbene or …

Taxol® Biosynthesis and Production: From Forests to Fermenters

C McElroy, S Jennewein - Biotechnology of natural products, 2018 - Springer
Taxol®(paclitaxel) has fascinated researchers, medical professionals, politicians and
entrepreneurs for almost half a century. Its medicinal value as a potent anti-cancer …

Constitutive expression of VviNAC17 transcription factor significantly induces the synthesis of flavonoids and other phenolics in transgenic grape berry cells

H Badim, M Vale, M Coelho, A Granell… - Frontiers in plant …, 2022 - frontiersin.org
VviNAC17 is a grapevine transcription factor activated by ABA. Because ABA has been
proposed as the main signal modulating the secondary metabolism in grape berry skins …

The state-of-the-art of grapevine biotechnology and new breeding technologies (NBTS)

L Dalla Costa, M Malnoy, D Lecourieux, L Deluc… - Oeno One, 2019 - hal.science
Context of the review: The manipulation of the genetic basis controlling grapevine
adaptation and phenotypic plasticity can be performed either by classical genetics or …

Silybum marianum cell cultures stably transformed with Vitis vinifera stilbene synthase accumulate t‐resveratrol in the extracellular medium after elicitation with …

D Hidalgo, A Martínez‐Márquez… - Engineering in Life …, 2017 - Wiley Online Library
The growing demand for t‐resveratrol for industrial uses has generated considerable
interest in its production. Heterologous resveratrol production in plant cell suspensions …

A new strategy to enhance the biosynthesis of trans-resveratrol by overexpressing stilbene synthase gene in elicited Vitis vinifera cell cultures

M Chu, MA Pedreño, N Alburquerque, L Faize… - Plant Physiology and …, 2017 - Elsevier
In this work, transgenic lines of suspension cultured cells of Vitis vinifera cv. Monastrell
containing the plasmid pMOG800-sts have been obtained. The cell growth of these …

A Tau Class Glutathione-S-Transferase is Involved in Trans-Resveratrol Transport Out of Grapevine Cells

A Martínez-Márquez, MJ Martínez-Esteso… - Frontiers in Plant …, 2017 - frontiersin.org
Vitis vinifera cell cultures respond to pathogens and elicitors by synthesizing and
extracellularly accumulating stilbenoid phytoalexins. Large amounts of trans-resveratrol (tR) …

A simplified protocol for Agrobacterium-mediated transformation of cell suspension cultures of the model species Medicago truncatula A17

AC Ferreira, BA Rebelo, R Abranches - Plant Cell, Tissue and Organ …, 2023 - Springer
This manuscript describes a unique protocol for the rapid transformation of Medicago
truncatula A17 cell suspension cultures mediated by Agrobacterium tumefaciens. Medicago …