[HTML][HTML] Beyond the three-chamber test: toward a multimodal and objective assessment of social behavior in rodents

R Jabarin, S Netser, S Wagner - Molecular Autism, 2022 - Springer
Main In recent years, substantial advances in social neuroscience have been realized,
including the generation of numerous rodent models of autism spectrum disorder. Still, it can …

Mouse and rat ultrasonic vocalizations in neuroscience and neuropharmacology: State of the art and future applications

M Premoli, S Pietropaolo, M Wöhr… - European Journal of …, 2023 - Wiley Online Library
Mice and rats emit ultrasonic vocalizations (USVs), which may express their arousal and
emotional states, to communicate with each other. There is continued scientific effort to …

[HTML][HTML] Altered behavior, brain structure, and neurometabolites in a rat model of autism-specific maternal autoantibody exposure

MR Bruce, ACM Couch, S Grant, J McLellan, K Ku… - Molecular …, 2023 - nature.com
Maternal immune dysregulation is a prenatal risk factor for autism spectrum disorder (ASD).
Importantly, a clinically relevant connection exists between inflammation and metabolic …

Mechanisms of copy number variants in neuropsychiatric disorders: From genes to therapeutics

MP Forrest, P Penzes - Current opinion in neurobiology, 2023 - Elsevier
Copy number variants (CNVs) are genomic imbalances strongly linked to the aetiology of
neuropsychiatric disorders such as schizophrenia and autism. By virtue of their large size …

[HTML][HTML] Prototypical autism: New diagnostic criteria and asymmetrical bifurcation model

L Mottron, D Gagnon - Acta psychologica, 2023 - Elsevier
The current “autism spectrum” DSM 5 diagnostic criteria and autism standardized diagnostic
instruments promote considerable heterogeneity or clinical indecision and may be …

[HTML][HTML] Recent developments in autism genetic research: A scientometric review from 2018 to 2022

M Lim, A Carollo, D Dimitriou, G Esposito - Genes, 2022 - mdpi.com
Genetic research in Autism Spectrum Disorder (ASD) has progressed tremendously in
recent decades. Dozens of genetic loci and hundreds of alterations in the genetic sequence …

[HTML][HTML] Shank postsynaptic scaffolding proteins in autism spectrum disorder: Mouse models and their dysfunctions in behaviors, synapses, and molecules

S Jung, M Park - Pharmacological Research, 2022 - Elsevier
Postsynaptic scaffolding proteins, which are major components of the postsynaptic density
(PSD) at excitatory synapses, include Shank, PSD-95, A-kinase anchoring protein, Homer …

[HTML][HTML] Maternal immune activation affects socio-communicative behavior in adult rats

K Gzieło, D Piotrowska, E Litwa, P Popik, A Nikiforuk - Scientific reports, 2023 - nature.com
A wide body of evidence suggests a relationship between maternal immune activation (MIA)
and neurodevelopmental disorders such as autism spectrum disorder (ASD). Since social …

[HTML][HTML] The emerging role of flavonoids in autism spectrum disorder: a systematic review

R Savino, A Medoro, S Ali, G Scapagnini… - Journal of Clinical …, 2023 - mdpi.com
Although autism spectrum disorder (ASD) is a multifaceted neurodevelopmental syndrome,
accumulating evidence indicates that oxidative stress and inflammation are common …

[HTML][HTML] Transcriptional reprogramming restores UBE3A brain-wide and rescues behavioral phenotypes in an Angelman syndrome mouse model

H O'Geen, U Beitnere, MS Garcia, A Adhikari… - Molecular Therapy, 2023 - cell.com
Angelman syndrome (AS) is a neurogenetic disorder caused by the loss of ubiquitin ligase
E3A (UBE3A) gene expression in the brain. The UBE3A gene is paternally imprinted in brain …