Major depressive disorder (MDD) is a psychiatric disease of still poorly understood
molecular etiology. Extensive studies at different molecular levels point to a high complexity …

Major depressive disorder (MDD) is a common and complex mental disorder, that adversely
impacts an individual's quality of life, but its diagnosis and treatment are not accurately …

Adult neurogenesis occurs mainly in the subgranular zone of the hippocampal dentate gyrus
and the subventricular zone of the lateral ventricles. Evidence supports the critical role of …

PINK1-Parkin mediated mitophagy, a selective form of autophagy, represents one of the
most important mechanisms in mitochondrial quality control (MQC) via the clearance of …

Non-neovascular or dry age-related macular degeneration (AMD) is a multi-factorial disease
with degeneration of the aging retinal-pigmented epithelium (RPE). Lysosomes play a …

Inflammatory responses, manifested in excessive oxidative stress and microglia
overactivation, together with metal ion-triggered amyloid-beta (Aβ) deposition, are critical …

Exosomal release pathway and autophagy together maintain homeostasis and survival of
cells under stressful conditions. Autophagy is a catabolic process through which cell entities …

Ferroptosis plays an essential role in the development of diabetes and its complications,
suggesting potential therapeutic strategies targeting ferroptosis. Secretory autophagosomes …

The ability of neurons to rapidly remodel their synaptic structure and strength in response to
neuronal activity is highly conserved across species and crucial for complex brain functions …

Epilepsy is a neurological disease characterized by repeated seizures. Despite of that the
brain-derived neurotrophic factor (BDNF) is implicated in the pathogenesis of …