Considering cancer not only as malignant cells on their own but as a complex disease in
which tumor cells interact and communicate with their microenvironment has motivated the …

Childhood cancer is considered rare, corresponding to~ 3% of all malignant neoplasms in
the human population. The World Health Organization (WHO) reports a universal …

Neuroblastoma is the most common extracranial solid tumor in infants, arising from
developmentally stalled neural crest-derived cells. Driving tumor differentiation is a …

Purpose Hypoxia-inducible factor (HIF) is one of the critical components of the tumor
microenvironment that is involved in tumor development. HIF-1α functionally and physically …

In the last decade, the chicken chorioallantoic membrane (CAM) assay has been re-
discovered in cancer research to study the molecular mechanisms of anti-cancer drug …

Ovarian cancer is the deadliest gynecological malignancy of the reproductive organs in the
United States. Cyclin-dependent kinase 1 (CDK1) is an important cell cycle regulatory …

PURPOSE The National Cancer Institute-Children's Oncology Group Pediatric Molecular
Analysis for Therapy Choice trial assigned patients age 1-21 years with relapsed or …

Neuroblastoma (NB) is one of the most frequently occurring neurogenic extracranial solid
cancers in childhood and infancy. Over the years, many pieces of evidence suggested that …

The chorioallantoic membrane (CAM) can be used as a valuable research tool to examine
tumors. The CAM can be used to investigate processes such as migration, invasion, and …

Simple Summary Malignant pleural mesothelioma is a cancer of the lung lining, normally
caused by asbestos, that develops decades after exposure. Chemotherapy, and recently …