Adipose-tissue plasticity in health and disease
Adipose tissue, colloquially known as" fat," is an extraordinarily flexible and heterogeneous
organ. While historically viewed as a passive site for energy storage, we now appreciate that …
organ. While historically viewed as a passive site for energy storage, we now appreciate that …
Adipose tissue at single-cell resolution
Adipose tissue exhibits remarkable plasticity with capacity to change in size and cellular
composition under physiological and pathophysiological conditions. The emergence of …
composition under physiological and pathophysiological conditions. The emergence of …
Interleukin-33 (IL-33): A critical review of its biology and the mechanisms involved in its release as a potent extracellular cytokine
C Cayrol, JP Girard - Cytokine, 2022 - Elsevier
Abstract Interleukin-33 (IL-33), a member of the IL-1 family, is an alarmin cytokine with
crucial roles in tissue homeostasis and repair, type 2 immunity, allergic and non-allergic …
crucial roles in tissue homeostasis and repair, type 2 immunity, allergic and non-allergic …
[HTML][HTML] Plasticity of epididymal adipose tissue in response to diet-induced obesity at single-nucleus resolution
AK Sárvári, EL Van Hauwaert, LK Markussen… - Cell metabolism, 2021 - cell.com
Adipose tissues display a remarkable ability to adapt to the dietary status. Here, we have
applied single-nucleus RNA-seq to map the plasticity of mouse epididymal white adipose …
applied single-nucleus RNA-seq to map the plasticity of mouse epididymal white adipose …
Contribution of adipogenesis to healthy adipose tissue expansion in obesity
L Vishvanath, RK Gupta - The Journal of clinical …, 2019 - Am Soc Clin Investig
The manner in which white adipose tissue (WAT) expands and remodels directly impacts the
risk of developing metabolic syndrome in obesity. Preferential accumulation of visceral WAT …
risk of developing metabolic syndrome in obesity. Preferential accumulation of visceral WAT …
The mesenchymal context in inflammation, immunity and cancer
Mesenchymal cells are mesoderm-derived stromal cells that are best known for providing
structural support to organs, synthesizing and remodeling the extracellular matrix (ECM) and …
structural support to organs, synthesizing and remodeling the extracellular matrix (ECM) and …
Single-cell transcriptome analysis of human skin identifies novel fibroblast subpopulation and enrichment of immune subsets in atopic dermatitis
H He, H Suryawanshi, P Morozov… - Journal of Allergy and …, 2020 - Elsevier
Background Atopic dermatitis (AD) is a prevalent inflammatory skin disease with a complex
pathogenesis involving immune cell and epidermal abnormalities. Despite whole tissue …
pathogenesis involving immune cell and epidermal abnormalities. Despite whole tissue …
Tissue regulatory T cells: regulatory chameleons
AR Muñoz-Rojas, D Mathis - Nature Reviews Immunology, 2021 - nature.com
Abstract The FOXP3+ CD4+ regulatory T (Treg) cells located in non-lymphoid tissues differ
in phenotype and function from their lymphoid organ counterparts. Tissue Treg cells have …
in phenotype and function from their lymphoid organ counterparts. Tissue Treg cells have …
Single-cell dissection of the obesity-exercise axis in adipose-muscle tissues implies a critical role for mesenchymal stem cells
Exercise training is critical for the prevention and treatment of obesity, but its underlying
mechanisms remain incompletely understood given the challenge of profiling …
mechanisms remain incompletely understood given the challenge of profiling …
Emerging functions of IL-33 in homeostasis and immunity
GK Dwyer, LM D'Cruz… - Annual review of …, 2022 - annualreviews.org
Our understanding of the functions of the IL-1 superfamily cytokine and damage-associated
molecular pattern IL-33 continues to evolve with our understanding of homeostasis and …
molecular pattern IL-33 continues to evolve with our understanding of homeostasis and …