Drugging the efferocytosis process: concepts and opportunities

P Mehrotra, KS Ravichandran - Nature reviews Drug discovery, 2022 - nature.com
The daily removal of billions of apoptotic cells in the human body via the process of
efferocytosis is essential for homeostasis. To allow for this continuous efferocytosis, rapid …

[HTML][HTML] The non-canonical effects of heme oxygenase-1, a classical fighter against oxidative stress

J Wu, S Li, C Li, L Cui, J Ma, Y Hui - Redox biology, 2021 - Elsevier
The role of heme oxygenase-1 in resisting oxidative stress and cell protection has always
been a hot research topic. With the continuous deepening of research, in addition to directly …

c-MAF, a Swiss army knife for tolerance in lymphocytes

C Imbratta, H Hussein, F Andris, G Verdeil - Frontiers in immunology, 2020 - frontiersin.org
Beyond its well-admitted role in development and organogenesis, it is now clear that the
transcription factor c-Maf has owned its place in the realm of immune-related transcription …

Mycobacterial infection-induced miR-206 inhibits protective neutrophil recruitment via the CXCL12/CXCR4 signalling axis

K Wright, K de Silva, KM Plain, AC Purdie… - PLoS …, 2021 - journals.plos.org
Pathogenic mycobacteria actively dysregulate protective host immune signalling pathways
during infection to drive the formation of permissive granuloma microenvironments. Dynamic …

Inhibiting BTB domain and CNC homolog 1 (Bach1) as an alternative to increase Nrf2 activation in chronic diseases

D Mafra, L Alvarenga, LFMF Cardozo… - … et Biophysica Acta (BBA …, 2022 - Elsevier
BTB and CNC homology 1 (Bach1) is a protein that forms nuclear heterodimers with the
small musculoaponeurotic fibrosarcoma (sMaf). These bind to genomic DNA, promoting the …

Immune regulation and emerging roles of noncoding RNAs in Mycobacterium tuberculosis infection

S Liang, J Ma, H Gong, J Shao, J Li, Y Zhan… - Frontiers in …, 2022 - frontiersin.org
Tuberculosis, caused by Mycobacterium tuberculosis, engenders an onerous burden on
public hygiene. Congenital and adaptive immunity in the human body act as robust …

Advances of Long Non-Coding RNAs as Potential Biomarkers for Tuberculosis: New Hope for Diagnosis?

J Xia, Y Liu, Y Ma, F Yang, Y Ruan, JF Xu, J Pi - Pharmaceutics, 2023 - mdpi.com
Tuberculosis (TB), one of the top ten causes of death globally induced by the infection of
Mycobacterium tuberculosis (Mtb), remains a grave public health issue worldwide. With …

The Roles of Host Noncoding RNAs in Mycobacterium tuberculosis Infection

L Wei, K Liu, Q Jia, H Zhang, Q Bie… - Frontiers in …, 2021 - frontiersin.org
Tuberculosis remains a major health problem. Mycobacterium tuberculosis, the causative
agent of tuberculosis, can replicate and persist in host cells. Noncoding RNAs (ncRNAs) …

Evaluation of Berberine as an Adjunct to TB Treatment

M Ozturk, JE Chia, R Hazra, M Saqib… - Frontiers in …, 2021 - frontiersin.org
Tuberculosis (TB) is the global health problem with the second highest number of deaths
from a communicable disease after COVID-19. Although TB is curable, poor health …

[HTML][HTML] The role of non-coding RNA on macrophage modification in tuberculosis infection

Z Wang, H Xu, Z Wei, Y Jia, Y Wu, X Qi, Y Li… - Microbial Pathogenesis, 2020 - Elsevier
Tuberculosis (TB), a serious disease caused by Mycobacterium tuberculosis (Mtb), remains
the world's top infectious killer. It is well-established that TB can circumvent the host's …