Cellular signaling networks are the foundation which determines the fate and function of
cells as they respond to various cues and stimuli. The discovery of fluorescent proteins over …

Focal adhesion kinase (FAK), a non-receptor tyrosine kinase, is overexpressed and
activated in many cancer types. FAK regulates diverse cellular processes, including growth …

Focal adhesion kinase (FAK) is a cytoplasmic protein tyrosine kinase that is overexpressed
and activated in several advanced-stage solid cancers. FAK promotes tumour progression …

Cell migration affects all morphogenetic processes and contributes to numerous diseases,
including cancer and cardiovascular disease. For most cells in most environments …

Focal adhesion kinase (FAK) is a key regulator of growth factor receptor-and integrin-
mediated signals, governing fundamental processes in normal and cancer cells through its …

FAK is a tyrosine kinase overexpressed in cancer cells and plays an important role in the
progression of tumors to a malignant phenotype. Except for its typical role as a cytoplasmic …

Optogenetic and chemogenetic control of proteins has revealed otherwise inaccessible
facets of signaling dynamics. Here, we use light-or ligand-sensitive domains to modulate the …

Focal adhesion kinase (FAK) is a non-receptor tyrosine kinase with key roles in the
regulation of cell adhesion migration, proliferation and survival. In cancer FAK is a major …

Cellular interactions with extracellular matrix play essential roles in tumor initiation,
progression and metastasis. Focal adhesion kinase (FAK) is a cytoplasmic tyrosine kinase …

Focal adhesion kinase (FAK) is a scaffold and tyrosine kinase protein that binds to itself and
cellular partners through its four-point-one, ezrin, radixin, moesin (FERM) domain. Recent …