Monitoring kinetic processes of drugs and metabolites: Surface-enhanced Raman spectroscopy

Z Luo, H Chen, X Bi, J Ye - Advanced Drug Delivery Reviews, 2024 - Elsevier
Monitoring the kinetic changes of drugs and metabolites plays a crucial role in fundamental
research, preclinical and clinical application. Raman spectroscopy (RS) is regarded as a …

[HTML][HTML] Advancing cryptococcal treatment: The role of nanoparticles in mitigating antifungal resistance

RH Lathakumari, LK Vajravelu, A Satheesan… - Current Research in …, 2024 - Elsevier
Cryptococcus, a ubiquitous and formidable fungal pathogen, contributes to a substantial
global disease burden, with nearly 250,000 cases and 181,000 fatalities attributed to …

[HTML][HTML] Is Cryptococcus neoformans a pleomorphic fungus?

JCS Brown, ER Ballou - Current opinion in microbiology, 2024 - Elsevier
Highlights•Morphotypes are defined as transcriptionally distinct, stable, heritable growth
types.•Cryptococcus neoformans exhibits at least three morphotypes relevant to …

Recent Progress in Mushroom-Derived Ergothioneine: Techniques and Applications

Y Weng, M Zhu, H Ma, X Hu, L Ren - Food Bioscience, 2024 - Elsevier
Ergothioneine (EGT), a vital naturally occurring water-soluble sulfur-containing amino acid
and potent antioxidant, serves as one of the primary bioactive compounds found in …

Exploring emerging drug responses in Cryptococcus

W Liu, Y Gao, C Ding - Trends in Microbiology, 2024 - cell.com
Cryptococcosis imposes a considerable burden on public health, and emerging drug
responses to anticryptococcal drugs remain to be addressed. In this forum article we discuss …

Population heterogeneity in Cryptococcus neoformans: Impact on pathogenesis

R Agrawal, RJA de Castro, A Sturny-Leclère… - PLoS …, 2024 - journals.plos.org
Cryptococcus neoformans was first isolated from a patient in 1894 [1] and 130 years later, it
remains a prevalent global threat, especially for people living with human immunodeficiency …

Unveiling genome plasticity as a mechanism of non-antifungal-induced antifungal resistance in Cryptococcus neoformans

L Zheng, Y Xu, L Guo - Frontiers in Microbiology, 2024 - frontiersin.org
Cryptococcus neoformans, a critical priority pathogen designated by the World Health
Organization, poses significant therapeutic challenges due to the limited availability of …

Phenotypic heterogeneity in bacteria: the rise of antibiotic persistence, clinical implications, and therapeutic opportunities

S Pani, SS Mohapatra - Archives of Microbiology, 2024 - Springer
The rising incidence of antimicrobial resistance (AMR) and the diminishing antibiotics
discovery pipeline have created an unprecedented scenario where minor infections could …

Penetration Profile of Terbinafine Compared to Amorolfine in Mycotic Human Toenails Quantified by Matrix-Assisted Laser Desorption Ionization–Fourier Transform …

N Joly-Tonetti, R Legouffe, A Tomezyk… - Infectious Diseases and …, 2024 - Springer
Introduction Amorolfine 5% lacquer is an established topical treatment for fungal infection of
the nails. The success of topical therapy for onychomycosis depends on whether the …

[PDF][PDF] Antidepressant Sertraline Modulates the Gene Expression and Alternative Splicing Events in the Dermatophyte Trichophyton rubrum: A Comprehensive …

CHL Rocha, FMG Rocha, PR Sanches, A Rossi… - 2024 - preprints.org
Background/Objectives: Dermatophytosis, a prevalent fungal infection of keratinized tissues,
is primarily caused by the filamentous fungus Trichophyton rubrum. Sertraline (SRT), an …