Human cytomegalovirus (HCMV) is a beta herpesvirus that establishes a life-long
persistence in the host, like all herpesviruses, by way of a latent infection. During latency …

Increasing evidence suggests that microorganisms might represent at least highly
interesting cofactors in colorectal cancer (CRC) oncogenesis and progression. Still …

Viral macrodomains possess the ability to counteract host ADP-ribosylation, a post-
translational modification implicated in the creation of an antiviral environment via immune …

Cytomegalovirus infection contributes to 10–30% of congenital hearing loss in children.
Vertebrate peripheral auditory organs include the outer, middle, and inner ear. Their …

Tankyrases are the group of enzymes belonging to a class of Poly (ADP-ribose) polymerase
(PARP) recently named ADP-ribosyltransferase (ARTD). The two isoforms of tankyrase ie …

Declines in cellular nicotinamide adenine dinucleotide (NAD) contribute to metabolic
dysfunction, increase susceptibility to disease, and occur as a result of pathogenic infection …

The antimalarial agents artemisinins inhibit cytomegalovirus (CMV) in vitro and in vivo, but
their target (s) has been elusive. Using a biotin-labeled artemisinin, we identified the …

Due to the frequent mutations, influenza A virus (IAV) becomes resistant to anti‐viral drugs
targeting influenza viral proteins. There are increasing interests in anti‐viral agents that …

Simple Summary Oncolytic viruses can be a potent tool in the fight against cancer. However,
in clinical settings their ability to replicate in and kill tumors is often limited. Combinations …

Human cytomegalovirus (HCMV) latency, the means by which the virus persists indefinitely
in an infected individual, is a major frontier of current research efforts in the field. Towards …