Brain Corticosteroid Receptor Balance in Health and Disease* | Endocrine Reviews | Oxford
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Signs and symptoms that are characteristic for depression include changes in the setpoint of
the hypothalamic-pituitary-adrenocortical (HPA) system, which in the majority of these …

Pannexin-1 (Panx1) plays a role in the release of ATP and glutamate in neurons and
astrocytes. Panx1 can be opened at the resting membrane potential by extracellular ATP via …

The fetus may be exposed to increased endogenous glucocorticoid or synthetic
glucocorticoid in late gestation. Approximately 7% of pregnant women in Europe and North …

Glia are now recognized as important contributors in pathological pain creation and
maintenance. Spinal cord glia exhibit extensive gap junctional connectivity, raising the …

The endocrine hypothalamus constitutes those cells which project to the median eminence
and secrete neurohormones into the hypophysial portal blood to act on cells of the anterior …

The aim of the present experiment was to study the effects of early postnatal maternal
separation on behavioural and adrenocortical responses to novelty in rats tested as adults …

Aging is associated with a progressive decline in physical and cognitive functions. The
impact of age-dependent endocrine changes regulated by the central nervous system on the …

Dexamethasone poorly penetrates in brain. A tracer amount of [3HJ-dexamethasone
administered to adrenaleetomized rats or mice is poorly retained by glucocorticoid receptors …

Synthetic glucocorticoids (sGCs) are routinely used to treat women at risk of preterm labour
to promote fetal lung maturation. There is now strong evidence that exposure to excess …