Recent developments in protease activity assays and sensors

ILH Ong, KL Yang - Analyst, 2017 - pubs.rsc.org
Proteases play a pivotal role in regulating important physiological processes from food
digestion to blood clotting. They are also important biomarkers for many diseases such as …

Mn-doped ZnS quantum dots–an effective nanoscale sensor

J Patel, B Jain, AK Singh, MABH Susan… - Microchemical …, 2020 - Elsevier
Quantum dots (QDs), due inter alia to their colourtunable symmetry, narrow emission, broad
absorption, stability, and solution processibility have received an upsurge of interest in the …

Ultrafast one-minute electronic detection of SARS-CoV-2 infection by 3CLpro enzymatic activity in untreated saliva samples

E Borberg, E Granot, F Patolsky - Nature Communications, 2022 - nature.com
Since its onset in December 2019, severe acute respiratory syndrome coronavirus 2, SARS-
CoV-2, has caused over 6.5 million deaths worldwide as of October 2022. Attempts to curb …

Enriching Mn-doped ZnSe quantum dots onto mesoporous silica nanoparticles for enhanced fluorescence/magnetic resonance imaging dual-modal bio-imaging

R Zhou, S Sun, C Li, L Wu, X Hou… - ACS applied materials & …, 2018 - ACS Publications
Multimodal imaging is more suitable for disease diagnosis because of its ability to provide
more complementary and accurate information over single-mode imaging. Mn-doped …

Quantum dots

T Maxwell, MGN Campos, S Smith, M Doomra… - Nanoparticles for …, 2020 - Elsevier
Quantum dots (QDs) are semiconductor nanoparticles which exhibit size and composition-
dependent optical and electronic (optoelectronic) properties. QDs are ultrasmall, typically …

A fluorescence resonance energy transfer biosensor based on carbon dots and gold nanoparticles for the detection of trypsin

S Xu, F Zhang, L Xu, X Liu, P Ma, Y Sun, X Wang… - Sensors and Actuators B …, 2018 - Elsevier
Herein we propose a fluorescence turn-on strategy for the sensitive and selective detection
of trypsin based on fluorescence resonance energy transfer (FRET) between gold …

Exploring the tunable excitation of QDs to maximize the overlap with the absorber for inner filter effect-based phosphorescence sensing of alkaline phosphatase

J Zhang, X Lu, Y Lei, X Hou, P Wu - Nanoscale, 2017 - pubs.rsc.org
The inner filter effect (IFE) is an effective way for fluorescence modulation and thus has been
extensively explored for the development of fluorescence assays. Theoretically, the key to …

Aggregation-induced emission enhancement of gold nanoclusters triggered by silicon nanoparticles for ratiometric detection of protamine and trypsin

F Xue, F Qu, W Han, L Xia, J You - Analytica Chimica Acta, 2019 - Elsevier
Metal nanoclusters protected by glutathione (GSH) have attracted a wide attention due to the
unique aggregation-induced emission (AIE) feature. However, the “trigger” effects of ethanol …

Ultrasensitive off-on-off fluorescent nanosensor for protamine and trypsin detection based on inner-filter effect between N, S-CDs and gold nanoparticles

Q Bao, D Lin, Y Gao, L Wu, J Fu, K Galaa, X Lin… - Microchemical …, 2021 - Elsevier
Herein we develop a novel “off–on-off” fluorescent nanosensor for the ultra-sensitive
detection of protamine and trypsin based on the as-prepared nitrogen and sulphur doped …

Sensitive fluorescence sensor for point-of-care detection of trypsin using glutathione-stabilized gold nanoclusters

H Li, M Yang, D Kong, R Jin, X Zhao, F Liu… - Sensors and Actuators B …, 2019 - Elsevier
There is an urgent demand for on-site detection of biomarker, particularly in clinical
diagnosis and therapeutics applications. Herein, we designed a convenient and sensitive …