Recent advances in the impurity profiling of drugs

D Bartos, S Gorog - Current Pharmaceutical Analysis, 2008 - ingentaconnect.com
Drug impurity profiling, ie identification, structure elucidation and quantitative determination
of impurities and degradation products in bulk drug materials and pharmaceutical …

Desirability-based optimization and its sensitivity analysis for the perindopril and its impurities analysis in a microemulsion LC system

A Malenović, Y Dotsikas, M Mašković… - Microchemical …, 2011 - Elsevier
In the current paper the application of multiobjective optimization (MOOP) technique, via
Derringer's desirability function, to a microemulsion liquid chromatographic (MELC) method …

[PDF][PDF] Analytical method development and validation of amlodipine besylate and perindopril erbumine in combine dosage form by RP-HPLC

J Prajapati, A Patel, MB Patel, N Prajapati… - … Journal of PharmTech …, 2011 - researchgate.net
The objective of this present work was to develop and validate analytical method for
quantitative determination of Perindopril Erbumine and Amlodipine Besylate in a tablet …

Validated chromatographic methods for determination of perindopril and amlodipine in pharmaceutical formulation in the presence of their degradation products

HE Zaazaa, SS Abbas, HAM Essam… - Journal of …, 2013 - academic.oup.com
Two specific, sensitive, and precise stability-indicating chromatographic methods have been
developed, optimized and validated for determination of perindopril arginin (PER) and …

Determination of absolute photoionization cross-sections of nitrogenous compounds

M Xie, Z Zhou, Z Wang, D Chen, F Qi - International Journal of Mass …, 2011 - Elsevier
The absolute photoionization cross-sections of 24 nitrogenous compounds were measured
in the photon energy range from their respective ionization thresholds to 11.5 eV, including n …

A Proline-Based Tectons and Supramolecular Synthons for Drug Design 2.0: A Case Study of ACEI

J Bojarska, M Remko, M Breza, I Madura, A Fruziński… - Pharmaceuticals, 2020 - mdpi.com
Proline is a unique, endogenous amino acid, prevalent in proteins and essential for living
organisms. It is appreciated as a tecton for the rational design of new bio-active substances …

Recent trends in impurity profiling and forced degradation of antihypertensive drugs

MN Salunkhe, SD Gite, RN Kachave - Journal of Liquid …, 2017 - Taylor & Francis
This review describes the recent trends in analytical perspectives of impurity profiling and
forced degradation of pharmaceutical drug and drug products used for the treatment of …

Assessment of liquid chromatographic method robustness by use of Plackett-Burman design

M Mašković, B Jančić-Stojanović… - Acta …, 2010 - akjournals.com
Robustness testing is an important part of method validation. Many ideas on robustness
testing can be found in the literature, but the most useful approach is application of …

[HTML][HTML] Kinetic spectrophotometric method for the determination of perindopril erbumine in pure and commercial dosage forms

N Rahman, H Rahman, SM Haque - Arabian Journal of Chemistry, 2017 - Elsevier
A kinetic spectrophotometric method has been developed for the determination of
perindopril erbumine in pure and commercial dosage forms. The method is based on the …

The Development and Validation of a Stability-Indicating UHPLC-DAD Method for Determination of Perindopril l-Arginine in Bulk Substance and Pharmaceutical …

M Paczkowska, P Zalewski, P Garbacki… - Chromatographia, 2014 - Springer
A stability-indicating ultra-high-performance liquid chromatography (UHPLC) method with a
diode array detector was developed and validated for the determination of cis/trans isomers …