DNA lesion bypass and the stochastic dynamics of transcription-coupled repair
MD Nicholson, CJ Anderson… - Proceedings of the …, 2024 - National Acad Sciences
DNA base damage is a major source of oncogenic mutations and disruption to gene
expression. The stalling of RNA polymerase II (RNAP) at sites of DNA damage and the …
expression. The stalling of RNA polymerase II (RNAP) at sites of DNA damage and the …
Deciphering the dynamic code: DNA recognition by transcription factors in the ever-changing genome
Transcription factors (TFs) intricately navigate the vast genomic landscape to locate and
bind specific DNA sequences for the regulation of gene expression programs. These …
bind specific DNA sequences for the regulation of gene expression programs. These …
Transcription Factors, Nucleotide Excision Repair, and Cancer: A Review of Molecular Interplay
PY Guneri-Sozeri, O Adebali - The International Journal of Biochemistry & …, 2024 - Elsevier
Bulky DNA adducts are mostly formed by external factors such as UV irradiation, smoking or
treatment with DNA crosslinking agents. If such DNA adducts are not removed by nucleotide …
treatment with DNA crosslinking agents. If such DNA adducts are not removed by nucleotide …
Nucleotide excision repair of aflatoxin-induced DNA damage within the 3D human genome organization
Abstract Aflatoxin B1 (AFB1), a potent mycotoxin, is one of the environmental risk factors that
cause liver cancer. In the liver, the bioactivated AFB1 intercalates into the DNA double helix …
cause liver cancer. In the liver, the bioactivated AFB1 intercalates into the DNA double helix …
[HTML][HTML] Time is ticking faster for long genes in aging
Recent studies of aging organisms have identified a systematic phenomenon, characterized
by a negative correlation between gene length and their expression in various cell types …
by a negative correlation between gene length and their expression in various cell types …