Vitamin K: double bonds beyond coagulation insights into differences between vitamin K1 and K2 in health and disease

M Halder, P Petsophonsakul, AC Akbulut… - International journal of …, 2019 - mdpi.com
Vitamin K is an essential bioactive compound required for optimal body function. Vitamin K
can be present in various isoforms, distinguishable by two main structures, namely …

Vitamins K1 and K2: the emerging group of vitamins required for human health

GK Schwalfenberg - Journal of nutrition and metabolism, 2017 - Wiley Online Library
Objective. To review the evidence for the use of vitamin K supplementation in clinical
conditions such as osteoporosis, vascular calcification, arthritis, cancer, renal calculi …

New insights into vitamin K biology with relevance to cancer

JE Welsh, MJ Bak, CJ Narvaez - Trends in molecular medicine, 2022 - cell.com
Phylloquinone (vitamin K1) and menaquinones (vitamin K2 family) are essential for post-
translational γ-carboxylation of a small number of proteins, including clotting factors. These …

Molecular pathways and roles for vitamin K2-7 as a health-beneficial nutraceutical: Challenges and opportunities

N Jadhav, S Ajgaonkar, P Saha, P Gurav… - Frontiers in …, 2022 - frontiersin.org
Vitamin K2-7, also known as menaquinone-7 (MK-7) is a form of vitamin K that has health-
beneficial effects in osteoporosis, cardiovascular disease, inflammation, cancer, Alzheimer's …

Vitamin K: New insights related to senescence and cancer metastasis

A Chen, J Li, N Shen, H Huang, Q Hang - Biochimica et Biophysica Acta …, 2024 - Elsevier
Several clinical trials and experimental studies have recently shown that vitamin K (VK)
supplementation benefits the human body. Specifically, VK participates in coagulation and is …

Research progress on the anticancer effects of vitamin K2

F Xv, J Chen, L Duan, S Li - Oncology letters, 2018 - spandidos-publications.com
Despite the availability of multiple therapeutic methods for patients with cancer, the long‑
term prognosis is not satisfactory in a number of different cancer types. Vitamin K2 (VK2) …

Vitamin K contribution to DNA damage—advantage or disadvantage? A Human Health Response

J Kaźmierczak-Barańska, BT Karwowski - Nutrients, 2022 - mdpi.com
Vitamin K is the common name for a group of compounds recognized as essential for blood
clotting. The group comprises phylloquinone (K1)—a 2-methyl-3-phytyl-1, 4 …

[HTML][HTML] Role of emerging vitamin K‑dependent proteins: Growth arrest‑specific protein 6, Gla‑rich protein and periostin

H Xiao, J Chen, L Duan, S Li - … journal of molecular …, 2021 - spandidos-publications.com
Vitamin K‑dependent proteins (VKDPs) are a group of proteins that need vitamin K to
conduct carboxylation. Thus far, scholars have identified a total of 17 VKDPs in the human …

[HTML][HTML] Vitamin K and its analogs: Potential avenues for prostate cancer management

S Dasari, SM Ali, G Zheng, A Chen, VS Dontaraju… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Epidemiological studies have demonstrated a relationship between cancer incidence and
dietary habits. Especially intake of certain essential nutrients like vitamins has been shown …

[PDF][PDF] Vitamin K contribution to DNA damage-advantage or disadvantage? a human health response

J Kazmierczak-Baranska, BT Karwowski - Nutrients, 2022 - pdfs.semanticscholar.org
Vitamin K is the common name for a group of compounds recognized as essential for blood
clotting. The group comprises phylloquinone (K1)—a 2-methyl-3-phytyl-1, 4 …