Breast Cancer is a complex disease characterized by the occurrence of multiple molecular alterations. Currently, some molecular markers are in use for breast cancer diagnostic …
VI Petkov, DP Miller, N Howlader, N Gliner, W Howe… - NPJ breast …, 2016 - nature.com
Abstract The 21-gene Recurrence Score assay is validated to predict recurrence risk and chemotherapy benefit in hormone-receptor-positive (HR+) invasive breast cancer. To …
Abstract Background The Oncotype DX breast recurrence score has been introduced more than a decade ago to aid physicians in determining the need for systemic adjuvant …
J Albanell, A Gonzalez, M Ruiz-Borrego, E Alba… - Annals of …, 2012 - Elsevier
Background This study examined the impact of the Recurrence Score (RS) in Spanish breast cancer patients and explored the associations between clinicopathological markers …
Gene expression profiles with prognostic capacities have shown good performance in multiple clinical trials. However, with multiple assays available and numerous types of …
S Ward, A Scope, R Rafia, A Pandor… - Health technology …, 2013 - eprints.whiterose.ac.uk
Gene expression profiling and expanded immunohistochemistry tests to guide the use of adjuvant chemotherapy in breast cancer man Page 1 DOI 10.3310/hta17440 HealtH tecHnology …
MJ Hassett, SM Silver, ME Hughes… - Journal of clinical …, 2012 - ascopubs.org
Purpose Gene expression profile (GEP) testing is a relatively new technology that offers the potential of personalized medicine to patients, yet little is known about its adoption into …
J Albanell, C Svedman, J Gligorov, SDH Holt… - European Journal of …, 2016 - Elsevier
Abstract Purpose The 21-gene Recurrence Score assay (Oncotype DX) provides prognostic/predictive information in oestrogen receptor positive (ER+) early breast cancer …
RC Stein, JA Dunn, JMS Bartlett… - Health Technology …, 2016 - ncbi.nlm.nih.gov
BACKGROUND There is uncertainty about the chemotherapy sensitivity of some oestrogen receptor (ER)-positive, human epidermal growth factor receptor 2 (HER2)-negative breast …