[HTML][HTML] Transcriptomics analysis reveals molecular alterations underpinning spaceflight dermatology

H Cope, J Elsborg, S Demharter, JT McDonald… - Communications …, 2024 - nature.com
Background Spaceflight poses a unique set of challenges to humans and the hostile
spaceflight environment can induce a wide range of increased health risks, including …

Genome and clonal hematopoiesis stability contrasts with immune, cfDNA, mitochondrial, and telomere length changes during short duration spaceflight

JS Garcia-Medina, K Sienkiewicz… - Precision Clinical …, 2024 - academic.oup.com
Abstract Background The Inspiration4 (I4) mission, the first all-civilian orbital flight mission,
investigated the physiological effects of short-duration spaceflight through a multi-omic …

Optimizing human performance in extreme environments through precision medicine: From spaceflight to high-performance operations on Earth

MA Schmidt, JA Jones, CE Mason - Cambridge Prisms: Precision …, 2023 - cambridge.org
Humans operating in extreme environments often conduct their operations at the edges of
the limits of human performance. Sometimes, they are required to push these limits to …

[HTML][HTML] Aging and putative frailty biomarkers are altered by spaceflight

A Camera, M Tabetah, V Castañeda, JK Kim… - Scientific Reports, 2024 - nature.com
Human space exploration poses inherent risks to astronauts' health, leading to molecular
changes that can significantly impact their well-being. These alterations encompass …

Molecular and physiologic changes in the SpaceX Inspiration4 civilian crew

CW Jones, EG Overbey, J Lacombe, AJ Ecker… - Nature, 2024 - nature.com
Human spaceflight has historically been managed by government agencies, such as the
NASA Twins Study1, but new commercial spaceflight opportunities have opened spaceflight …