Chemical glycoproteomics

KK Palaniappan, CR Bertozzi - Chemical reviews, 2016 - ACS Publications
Chemical tools have accelerated progress in glycoscience, reducing experimental barriers
to studying protein glycosylation, the most widespread and complex form of posttranslational …

Systems medicine: the future of medical genomics and healthcare

C Auffray, Z Chen, L Hood - Genome medicine, 2009 - Springer
High-throughput technologies for DNA sequencing and for analyses of transcriptomes,
proteomes and metabolomes have provided the foundations for deciphering the structure …

The diverse and expanding role of mass spectrometry in structural and molecular biology

P Lössl, M van de Waterbeemd, AJR Heck - The EMBO journal, 2016 - embopress.org
The emergence of proteomics has led to major technological advances in mass
spectrometry (MS). These advancements not only benefitted MS‐based high‐throughput …

Molecular signatures of obstructive sleep apnea in adults: a review and perspective

ES Arnardottir, M Mackiewicz, T Gislason, KL Teff… - Sleep, 2009 - academic.oup.com
The consequences of obstructive sleep apnea (OSA) are largely mediated by chronic
intermittent hypoxia and sleep fragmentation. The primary molecular domains affected are …

Statistical analysis of proteomics data: a review on feature selection

M Lualdi, M Fasano - Journal of proteomics, 2019 - Elsevier
The spread of “-omics” strategies has strongly changed the way of thinking about the
scientific method. Indeed, managing huge amounts of data imposes the replacement of the …

Crucial role of fatty acid oxidation in asthmatic bronchial smooth muscle remodelling

P Esteves, L Blanc, A Celle, I Dupin… - European …, 2021 - Eur Respiratory Soc
Background Bronchial smooth muscle (BSM) remodelling in asthma is related to an
increased mitochondrial biogenesis and enhanced BSM cell proliferation in asthma. Since …

The vacuolar H+/Ca transporter CAX1 participates in submergence and anoxia stress responses

J Yang, IE Mathew, H Rhein, R Barker, Q Guo… - Plant …, 2022 - academic.oup.com
A plant's oxygen supply can vary from normal (normoxia) to total depletion (anoxia).
Tolerance to anoxia is relevant to wetland species, rice (Oryza sativa) cultivation, and …

Understanding cervical cancer through proteomics

F Martínez-Rodríguez, JE Limones-González… - Cells, 2021 - mdpi.com
Cancer is one of the leading public health issues worldwide, and the number of cancer
patients increases every day. Particularly, cervical cancer (CC) is still the second leading …

[HTML][HTML] LC–MS based detection of differential protein expression

L Tuli, HW Ressom - Journal of proteomics & bioinformatics, 2009 - ncbi.nlm.nih.gov
While several techniques are available in proteomics, LC-MS based analysis of complex
protein/peptide mixtures has turned out to be a mainstream analytical technique for …

Glycoproteomics in neurodegenerative diseases

H Hwang, J Zhang, KA Chung… - Mass spectrometry …, 2010 - Wiley Online Library
Protein glycosylation regulates protein function and cellular distribution. Additionally,
aberrant protein glycosylations have been recognized to play major roles in human …